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Hypoglycemic and anticoagulant effects of tetrapeptide Pro-Gly-Pro-Leu in hypercholesterolemia.

作者信息

Shubina T A, Grigor'eva M E, Lyapina L A, Obergan T Yu, Myasoedov N F, Andreeva L A

机构信息

Laboratory of Blood Protective Systems, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia,

出版信息

Bull Exp Biol Med. 2014 Nov;158(1):30-3. doi: 10.1007/s10517-014-2684-9. Epub 2014 Nov 19.

Abstract

In rats with experimental hypercholesterolemia, 7-fold intranasal administration of the peptide Pro-Gly-Pro-Leu in a dose of 200 μg/kg body weight prevented the increase in blood glucose level and produced an anticoagulant effect.

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