Dunstan Matt J D, Molena Emma J, Ratnasingham Kumaran, Kamocka Anna, Smith Natasha C, Humadi Samer, Irukulla Shashi
Department of Bariatric Surgery, Ashford and St. Peter's Hospitals NHS Foundation Trust, Guildford Road, Chertsey, Surrey, KT16 0PZ, UK,
Obes Surg. 2015 Apr;25(4):648-55. doi: 10.1007/s11695-014-1425-5.
Bariatric surgery (including gastric bypass) is associated with long-term deficiencies in vitamins and minerals, which may have deleterious effects on physiology. The American Association of Clinical Endocrinologists' (AACE) guidelines regarding post-operative vitamin supplementation have recently been endorsed by the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO). Supplements have cost implications. Non-branded multivitamins may have similar compositions to branded multivitamins, but at a lower cost. This study assesses multivitamin supplementation following bariatric gastric bypass in England against AACE guidelines. It also examines the composition and cost of branded and non-branded multivitamins.
Micronutrient amounts in common multivitamin preparations were obtained from product literature. Costs were collected from a standard retailer. To determine vitamin prescribing patterns, the 37 NHS hospitals performing bariatric gastric bypasses in England were contacted. Practice was assessed against AACE guidelines.
All non-branded multivitamins met AACE guidelines for composition. Most had similar compositions to branded multivitamins, and all were cheaper. There was no standard practice regarding post-operative supplementation among the 35 responding hospitals. Only 7/35 (20%) hospitals followed the guidance for two-tablet doses of multivitamins. Immediately post-operatively, 25/35 (71%) hospitals administered calcium carbonate and vitamin D (none recommended calcium citrate, as recommended by AACE to improve absorption), and only 9/35 (26%) hospitals recommended iron to all patients.
Most non-branded multivitamins are lower cost alternatives to branded multivitamins, with similar compositions. The AACE recommendation for two-tablet doses of multivitamins is not being met by most English centres. Calcium and iron supplementation is also inadequate.
减肥手术(包括胃旁路手术)与维生素和矿物质的长期缺乏有关,这可能对生理机能产生有害影响。美国临床内分泌医师协会(AACE)关于术后维生素补充的指南最近已得到国际肥胖与代谢紊乱手术联合会(IFSO)的认可。补充剂会产生成本问题。非品牌多种维生素的成分可能与品牌多种维生素相似,但成本较低。本研究对照AACE指南评估了英国胃旁路减肥手术后多种维生素的补充情况。它还研究了品牌和非品牌多种维生素的成分和成本。
从产品说明书中获取常见多种维生素制剂中的微量营养素含量。从一家标准零售商处收集成本数据。为了确定维生素的处方模式,联系了在英国进行胃旁路减肥手术的37家国民保健服务(NHS)医院。根据AACE指南评估实际做法。
所有非品牌多种维生素的成分均符合AACE指南。大多数与品牌多种维生素成分相似,且都更便宜。在35家回复的医院中,术后补充维生素没有标准做法。只有7/35(20%)的医院遵循两片剂量多种维生素的指导。术后立即,25/35(71%)的医院给予碳酸钙和维生素D(没有一家按照AACE建议使用柠檬酸钙以提高吸收),只有9/35(26%)的医院向所有患者推荐铁剂。
大多数非品牌多种维生素是品牌多种维生素的低成本替代品,成分相似。大多数英国中心未达到AACE关于两片剂量多种维生素的建议。钙和铁的补充也不足。