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Cardiovascular endocrinology: Growth hormone in CVD prediction--a tall order?

作者信息

Tsao Connie W, Vasan Ramachandran S

机构信息

Cardiovascular Division, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, RW-453, Boston, MA 02215, USA.

The Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, MA 01702, USA.

出版信息

Nat Rev Endocrinol. 2015 Jan;11(1):11-3. doi: 10.1038/nrendo.2014.204. Epub 2014 Nov 18.

DOI:10.1038/nrendo.2014.204
PMID:25404017
Abstract
摘要

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本文引用的文献

1
Fasting levels of high-sensitivity growth hormone predict cardiovascular morbidity and mortality: the Malmö Diet and Cancer study.高敏生长激素的空腹水平可预测心血管疾病的发病率和死亡率：马尔默饮食与癌症研究
J Am Coll Cardiol. 2014 Oct 7;64(14):1452-60. doi: 10.1016/j.jacc.2014.03.063.
2
Potential new role of the GHSR-1a-mediated signaling pathway in cardiac remodeling after myocardial infarction (Review).GHSR-1a介导的信号通路在心肌梗死后心脏重塑中的潜在新作用（综述）
Oncol Lett. 2014 Sep;8(3):969-971. doi: 10.3892/ol.2014.2245. Epub 2014 Jun 12.
3
An assessment of the relationship between clinical utility and predictive ability measures and the impact of mean risk in the population.
对临床效用与预测能力指标之间的关系以及人群中平均风险的影响进行评估。
BMC Med Res Methodol. 2014 Jul 3;14:86. doi: 10.1186/1471-2288-14-86.
4
GH and the cardiovascular system: an update on a topic at heart.生长激素与心血管系统：这一心脏领域的热门话题最新进展
Endocrine. 2015 Feb;48(1):25-35. doi: 10.1007/s12020-014-0327-6. Epub 2014 Jun 28.
5
Measurement of human growth hormone by immunoassays: current status, unsolved problems and clinical consequences.免疫分析法测定人生长激素：现状、未解决的问题及临床后果
Growth Horm IGF Res. 2010 Feb;20(1):19-25. doi: 10.1016/j.ghir.2009.09.005. Epub 2009 Oct 8.
6
Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysis.2589例垂体功能减退性生长激素缺乏成人患者心血管风险的决定因素——一项KIMS数据库分析
Eur J Endocrinol. 2006 Jul;155(1):79-90. doi: 10.1530/eje.1.02179.
7
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span.小鼠生长激素受体的缺失而非拮抗作用会导致体重、胰岛素和胰岛素样生长因子I水平严重降低，并延长寿命。
Endocrinology. 2003 Sep;144(9):3799-810. doi: 10.1210/en.2003-0374.
8
Hypopituitary females have a high incidence of cardiovascular morbidity and an increased prevalence of cardiovascular risk factors.垂体功能减退的女性心血管疾病发病率高，心血管危险因素的患病率也有所增加。
J Clin Endocrinol Metab. 2000 Feb;85(2):574-84. doi: 10.1210/jcem.85.2.6346.
9
Growth hormone as a risk for premature mortality in healthy subjects: data from the Paris prospective study.生长激素与健康受试者过早死亡风险：来自巴黎前瞻性研究的数据。
BMJ. 1998 Apr 11;316(7138):1132-3. doi: 10.1136/bmj.316.7138.1132.