Amedee R, Klaeyle D, Mann W, Geyer H
Department of Otolaryngology, University of Freiburg Medical School, FRG.
ORL J Otorhinolaryngol Relat Spec. 1989;51(1):56-61. doi: 10.1159/000276032.
A series of 22 patients with histologically confirmed angiofibroma were treated primarily by surgical removal at the University of Freiburg ENT clinic during the 40-year period, 1946-1986. These tumors were staged according to size and extension on the basis of roentgenographic and surgical findings. Specific analysis of the operative approaches and recurrence rate by stage are included. Recurrent or residual disease was handled by surgical excision, irradiation, embolization, or a combination of these methods. The complication and morbidity rates were extremely low, while the mortality rate was zero. The tumor specimens received from the last 5 patients were evaluated for the presence of sex hormone receptors. No specific estrogen, progesterone or androgen receptors were detected in these tissues.
在1946年至1986年的40年期间，弗赖堡大学耳鼻喉科诊所对一系列22例经组织学确诊的血管纤维瘤患者主要采用手术切除治疗。这些肿瘤根据X线检查和手术结果按大小和范围进行分期。文中包含了按分期对手术方法和复发率的具体分析。复发性或残留性疾病通过手术切除、放疗、栓塞或这些方法的联合来处理。并发症和发病率极低，死亡率为零。对从最后5例患者获得的肿瘤标本进行了性激素受体检测。在这些组织中未检测到特异性雌激素、孕激素或雄激素受体。
