College of Automobile and Traffic Engineering, Nanjing Forestry University, Nanjing 210037, China ; Department of Mechanical Engineering, National University of Singapore, Singapore 117576.
Department of Mechanical Engineering, National University of Singapore, Singapore 117576.
Biomed Res Int. 2014;2014:408278. doi: 10.1155/2014/408278. Epub 2014 Oct 22.
This study is aimed at developing a high quality, validated finite element (FE) human head model for traumatic brain injuries (TBI) prediction and prevention during vehicle collisions. The geometry of the FE model was based on computed tomography (CT) and magnetic resonance imaging (MRI) scans of a volunteer close to the anthropometry of a 50th percentile male. The material and structural properties were selected based on a synthesis of current knowledge of the constitutive models for each tissue. The cerebrospinal fluid (CSF) was simulated explicitly as a hydrostatic fluid by using a surface-based fluid modeling method. The model was validated in the loading condition observed in frontal impact vehicle collision. These validations include the intracranial pressure (ICP), brain motion, impact force and intracranial acceleration response, maximum von Mises stress in the brain, and maximum principal stress in the skull. Overall results obtained in the validation indicated improved biofidelity relative to previous FE models, and the change in the maximum von Mises in the brain is mainly caused by the improvement of the CSF simulation. The model may be used for improving the current injury criteria of the brain and anthropometric test devices.
本研究旨在开发一种高质量、经过验证的有限元（FE）人类头部模型，用于预测和预防车辆碰撞中的创伤性脑损伤（TBI）。FE 模型的几何形状基于对志愿者的计算机断层扫描（CT）和磁共振成像（MRI）扫描，该志愿者的人体测量接近 50 百分位男性。基于对每种组织本构模型的现有知识的综合，选择了材料和结构特性。通过使用基于表面的流体建模方法，将脑脊液（CSF）明确模拟为静压流体。该模型在前部冲击车辆碰撞中观察到的加载条件下进行了验证。这些验证包括颅内压（ICP）、脑运动、冲击力和颅内加速度响应、大脑中的最大 von Mises 应力以及颅骨中的最大主应力。验证中获得的总体结果表明，与以前的 FE 模型相比，生物逼真度得到了提高，大脑中最大 von Mises 的变化主要是由于 CSF 模拟的改进。该模型可用于改进当前的大脑损伤标准和人体测量测试设备。
