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[主动脉疾病的诊断与治疗:2014年欧洲心脏病学会新指南]

[Diagnosis and treatment of aortic diseases : new guidelines of the European Society of Cardiology 2014].

作者信息

Eggebrecht H

机构信息

CCB - Cardioangiologisches Centrum Bethanien und AGAPLESION Bethanien-Krankenhaus, Im Prüfling 23, 60389, Frankfurt a. M., Deutschland,

出版信息

Herz. 2014 Dec;39(8):931-40. doi: 10.1007/s00059-014-4182-2.

DOI:10.1007/s00059-014-4182-2
PMID:25406331
Abstract

In September 2014 the European Society of Cardiology issued guidelines for the diagnosis and treatment of aortic diseases in adults. Contrast-enhanced computed tomography (CT) represents the imaging modality of first choice as it is rapidly and almost ubiquitously available and can evaluate the entire aorta in a single-step examination. In patients with a high clinical suspicion of an acute aortic syndrome based on (family) history and symptoms, CT should be performed without further delay to confirm or refute the diagnosis. Diseases involving the ascending aorta remain a domain of open surgery, be it on an emergency basis in an acute type A dissection or electively in asymptomatic aneurysms with an aortic diameter >5.5 cm. The presence of risk factors (e. g. bicuspid aortic valve, Marfan syndrome and aortic dissection/rupture in the family history) may prompt earlier surgical repair at a lower threshold diameter. The treatment of descending aortic disease is primarily conservative including modification of cardiovascular risk factors. If indicated, endovascular aortic stent graft repair appears to be superior to open surgery for descending thoracic aortic disease or equivalent in the treatment of infrarenal abdominal aortic aneurysms. The management of aortic diseases related to genetic connective tissue diseases (e. g. Marfan syndrome, Loeys-Dietz syndrome and Ehlers-Danlos syndrome) is complex and requires special multidisciplinary expertise.

摘要

2014年9月,欧洲心脏病学会发布了成人主动脉疾病的诊断和治疗指南。对比增强计算机断层扫描(CT)是首选的成像方式,因为它快速且几乎随处可得,并且可以在一次检查中评估整个主动脉。对于基于(家族)病史和症状高度怀疑急性主动脉综合征的患者,应立即进行CT检查以确诊或排除诊断。累及升主动脉的疾病仍然是开放手术的领域,无论是在急性A型夹层的紧急情况下,还是在主动脉直径>5.5 cm的无症状动脉瘤的择期手术中。存在危险因素(例如二叶主动脉瓣、马凡综合征和家族史中的主动脉夹层/破裂)可能会促使在较低的阈值直径时更早进行手术修复。降主动脉疾病的治疗主要是保守治疗,包括改变心血管危险因素。如果有指征,对于降主动脉疾病,血管内主动脉支架移植物修复似乎优于开放手术,对于肾下腹主动脉瘤的治疗效果相当。与遗传性结缔组织疾病(例如马凡综合征、洛伊茨-迪茨综合征和埃勒斯-当洛综合征)相关的主动脉疾病的管理很复杂,需要特殊的多学科专业知识。

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引用本文的文献

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本文引用的文献

1
2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC).2014年欧洲心脏病学会(ESC)主动脉疾病诊断和治疗指南:涵盖成人胸主动脉和腹主动脉急慢性疾病的文件。欧洲心脏病学会(ESC)主动脉疾病诊断和治疗特别工作组。
Eur Heart J. 2014 Nov 1;35(41):2873-926. doi: 10.1093/eurheartj/ehu281. Epub 2014 Aug 29.
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Diagnosis of acute aortic syndromes : imaging and beyond.急性主动脉综合征的诊断:影像学及其他方面
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主动脉壁内血肿:发病机制的相关方面(2011年)
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Penetrating aortic ulcer: defining risks and therapeutic strategies.穿透性主动脉溃疡:定义风险与治疗策略
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