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[查尔斯·米勒·费希尔:神经学观察大师]

[Charles Miller Fisher: the grandmaster of neurological observation].

作者信息

Fukutake Toshio

机构信息

Department of Neurology, Kameda Medical Center.

出版信息

Brain Nerve. 2014 Nov;66(11):1317-25. doi: 10.11477/mf.1416200034.

Abstract

Charles Miller Fisher is widely regarded as the father of modern stroke neurology. He discovered almost all pathomechanisms of cerebral infarction, including embolism from atrial fibrillation, carotid artery disease, and lacunar infarcts and their syndromes, by the most meticulous clinico-pathological observations. Moreover, his work provided the basis for treatments such as anticoagulation, antiplatelet therapy, and carotid endarterectomy. He also contributed greatly to several topics of General Neurology; for example, migraine, normal pressure hydrocephalus, and Miller Fisher syndrome. In his late years, he tried to expand the neurological field to the more complex disorders of human behavior, including hysteria, dementia, and ill-defined pain syndromes. He thus became known as the grandmaster of refined neurological observation. His lifelong detailed studies were crucially important in helping neurologists all over the world recognize disorders and syndromes that had not previously been understood.

摘要

查尔斯·米勒·费希尔被广泛认为是现代中风神经学之父。他通过最为细致的临床病理观察,发现了脑梗死几乎所有的发病机制,包括房颤引起的栓塞、颈动脉疾病、腔隙性梗死及其综合征。此外,他的工作为抗凝、抗血小板治疗以及颈动脉内膜切除术等治疗方法奠定了基础。他还对普通神经学的多个主题做出了巨大贡献;例如,偏头痛、正常压力脑积水和米勒·费希尔综合征。在晚年,他试图将神经学领域扩展到人类行为的更复杂疾病,包括癔症、痴呆和不明疼痛综合征。因此,他被誉为精细神经学观察的大师。他一生的详细研究对于帮助世界各地的神经学家认识以前未被理解的疾病和综合征至关重要。

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