Xiang Jiannan, Yuan Rui, Wang Ruijia, Yi Niannian, Lu Linghui, Zou Huaxu, He Weimin
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University , Changsha, 410082, P. R. China.
J Org Chem. 2014 Dec 5;79(23):11378-82. doi: 10.1021/jo501776b. Epub 2014 Nov 19.
The highly stereoselective bromination of alkynes has been realized by using copper(II) bromide as both the reacting partner and the catalyst, offering a generally efficient synthesis of (E)-dibromoalkenes. The reaction conditions are exceptionally mild, and a wide range of functional groups are well tolerated.
通过使用溴化铜作为反应试剂和催化剂，实现了炔烃的高度立体选择性溴化反应，为（E）-二溴烯烃提供了一种普遍有效的合成方法。该反应条件异常温和，并且对多种官能团具有良好的耐受性。
