Gatta Michela, Balottin Laura, Salmaso Ambra, Stucchi Manuela, DE Carlo Debora, Guarneri Elisa, Mannarini Stefania, Vecchi Marilena, Boniver Clementina, Battistella Pier A
Childhood, Adolescence and Family Unit, ULSS 16 and Department of Woman's and Child's Health, University of Padua, Padua, Italy.
Interdepartmental Center for Family Research, Department of Philosophy, Sociology, Education, and Applied Psychology, Section of Applied Psychology, University of Padua, Padua, Italy -
Minerva Pediatr. 2017 Feb;69(1):1-14. doi: 10.23736/S0026-4946.16.04163-3. Epub 2014 Nov 19.
The aim of this study was to describe the distribution, timing, and risk factors for psychopathology and to further examine the quality of life (QoL) in an Italian sample of children with recent onset epilepsy. Sociodemographic and psychosocial variables, family factors, as well as illness-related factors themselves were examined in order to clarify the relationship among these variables, psychopathology and QoL.
For this purpose, 49 children and adolescents (4-18 years), consecutively referred to a Neurophysiology Service, were evaluated by a multidisciplinary team using dimensional as well as categorical instruments both self-administered (self-report and proxy-report) and interviewer administered.
Forty-five percent of the patients exhibited one or more Axis I disorders (DSM-IV) when evaluated with K-SADS-PL interview. It's worth noting that preadolescent and adolescent patients tend to underestimate their problems compared to their parents'opinion, when answering self-administer questionnaires. Self-reported QoL appeared to be generally satisfactory. Social and family factor, as well as epilepsy related factors appeared to be linked both to the presence of psychopathology and to the QoL. Patients affected by psychiatric disorders exhibited the poorest QoL.
Also after many years from the onset, childhood epilepsy frequently fosters negative consequences in terms of social life, work, psychopathology and life expectancy. The ability of health services and public health measures to prevent and treat psychiatric comorbidity may have a pivotal role in enhancing patients' QoL.
本研究旨在描述意大利近期发病的癫痫患儿样本中精神病理学的分布、发生时间及风险因素，并进一步考察其生活质量（QoL）。研究对社会人口统计学和心理社会变量、家庭因素以及疾病相关因素本身进行了考察，以阐明这些变量、精神病理学和生活质量之间的关系。
为此，对49名4至18岁连续转诊至神经生理学服务部门的儿童和青少年，由多学科团队使用自评（自我报告和代理报告）及访谈者施测的维度和分类工具进行评估。
使用K-SADS-PL访谈进行评估时，45%的患者表现出一种或多种轴I障碍（DSM-IV）。值得注意的是，在回答自评问卷时，与父母的看法相比，青春期前和青春期患者往往低估自己的问题。自我报告的生活质量总体上似乎令人满意。社会和家庭因素以及癫痫相关因素似乎与精神病理学的存在和生活质量都有关联。患有精神疾病的患者生活质量最差。
即使在发病多年后，儿童癫痫在社会生活、工作、精神病理学和预期寿命方面仍经常产生负面后果。卫生服务和公共卫生措施预防和治疗精神疾病共病的能力，可能在提高患者生活质量方面发挥关键作用。
