Kashinath K, Reddy D Srinivasa
Division of Organic Chemistry, National Chemical Laboratory, Pune, Maharashtra, India.
Org Biomol Chem. 2015 Jan 28;13(4):970-3. doi: 10.1039/c4ob02143f. Epub 2014 Nov 14.
Multiple reactions in one pot has always been a useful technique for synthetic organic chemists, as it can minimizes solvent usage, time and the number of purification steps when compared to individual multi-step syntheses. In line with this, here in this perspective we discuss a one-pot quadruple/triple reaction sequence comprising an enyne ring-closing metathesis/cross-metathesis/Diels-Alder/aromatization for the synthesis of natural products setting.
一锅多反应一直是有机合成化学家常用的技术，因为与单独的多步合成相比，它可以减少溶剂用量、时间和纯化步骤的数量。与此一致，在本文中，我们从这个角度讨论了一个一锅四重/三重反应序列，该序列包括烯炔闭环复分解/交叉复分解/狄尔斯-阿尔德/芳构化反应，用于天然产物合成。
