Zehtabi-Oskuie Ana, Zinck Aurora A, Gelfand Ryan M, Gordon Reuven
Electrical and Computer Engineering, University of Victoria, Victoria, BC, Canada.
Nanotechnology. 2014 Dec 12;25(49):495301. doi: 10.1088/0957-4484/25/49/495301. Epub 2014 Nov 19.
Double nanohole (DNH) laser tweezers can optically trap and manipulate objects such as proteins, nanospheres, and other nanoparticles; however, precise fabrication of those DNHs has been expensive with low throughput. In this work, template stripping was used to pattern DNHs with gaps as small as 7 nm, in optically thick Au films. These DNHs were used to trap streptavidin as proof of operation. The structures were processed multiple times from the same template to demonstrate reusability. Template stripping is a promising method for high-throughput, reproducible, and cost efficient fabrication of DNH apertures for optical trapping.
双纳米孔（DNH）激光镊子可以光学捕获和操纵蛋白质、纳米球和其他纳米颗粒等物体；然而，精确制造这些双纳米孔成本高昂且产量低。在这项工作中，采用模板剥离技术在光学厚度的金膜中制作了间隙小至7纳米的双纳米孔。这些双纳米孔被用于捕获链霉亲和素以证明其可操作性。从同一模板对结构进行多次加工以证明其可重复使用性。模板剥离是一种很有前景的方法，可用于高通量、可重复且经济高效地制造用于光学捕获的双纳米孔孔径。
