Poltavtseva R A, Nikonova Yu A, Selezneva I I, Yaroslavtseva A K, Stepanenko V N, Esipov R S, Pavlovich S V, Klimantsev I V, Tyutyunnik N V, Grebennik T K, Nikolaeva A V, Sukhikh G T
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia,
Bull Exp Biol Med. 2014 Nov;158(1):164-9. doi: 10.1007/s10517-014-2714-7. Epub 2014 Nov 19.
We studied cell cultures isolated from the pulp of third molar germ of an adult human and from the skin of a human fetus on gestation day 10. Both cultures expressed similar repertoire of surface markers typical of multipotent mesenchymal cells (CD44, CD90, and CD105). Under in vitro conditions, dental pulp cells were more susceptible to factors inducing their differentiation into adipogenic, chondrogenic, and osteogenic lineage cells.
我们研究了从一名成年人类第三磨牙牙胚的牙髓以及妊娠第10天的人类胎儿皮肤中分离出的细胞培养物。两种培养物均表达了多能间充质细胞典型的相似表面标志物谱（CD44、CD90和CD105）。在体外条件下，牙髓细胞更容易受到诱导其分化为脂肪生成、软骨生成和成骨谱系细胞的因子的影响。
