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经导管动脉化疗栓塞治疗肝细胞癌继发脊髓缺血

Spinal cord ischemia secondary to transcatheter arterial chemoembolization for hepatocellular carcinoma.

作者信息

Bazine Aziz, Fetohi Mohamed, Berri Maha Ait, Essaadi Ismail, Elbakraoui Kamal, Ichou Mohamed, Errihani Hassan

机构信息

Department of Medical Oncology, Military Hospital My Ismail, Meknès.

Departments of Neurology, Military Hospital Med V, Rabat, Morocco.

出版信息

Case Rep Gastroenterol. 2014 Sep 10;8(3):264-9. doi: 10.1159/000368075. eCollection 2014 Sep.

Abstract

Transcatheter arterial chemoembolization (TACE) is accepted worldwide as an effective treatment for patients with unresectable hepatocellular carcinoma. Although considered relatively safe, TACE has been associated with several complications. Spinal cord ischemia secondary to TACE is an extremely rare but disastrous complication. We report a very rare case of spinal cord injuries after TACE, together with a literature review. During the procedure, the patient suddenly experienced sensory impairment below the T10 dermatome and bilateral lower extremity motor weakness. She was given high-dose steroids and supportive therapy. The sensory deficits nearly improved completely, but motor strength remained unchanged. Thereafter, a chest computed tomography scan showed tumor metastasis to the lungs. The patient is now receiving sorafenib and follow-up.

摘要

经导管动脉化疗栓塞术(TACE)作为不可切除肝细胞癌患者的一种有效治疗方法在全球范围内被广泛接受。尽管TACE被认为相对安全,但仍会引发多种并发症。TACE继发的脊髓缺血是一种极其罕见但灾难性的并发症。我们报告了1例TACE术后脊髓损伤的罕见病例,并进行文献复习。术中,患者突然出现T10皮节以下感觉障碍及双下肢运动无力。给予患者大剂量类固醇及支持治疗。感觉障碍几乎完全改善,但肌力仍无变化。此后,胸部计算机断层扫描显示肺部有肿瘤转移。该患者目前正在接受索拉非尼治疗并进行随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/117e/4209262/f9abe11e1755/crg-0008-0264-g01.jpg

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