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经动脉化疗栓塞治疗肝细胞癌后发生脊髓梗死:一例报告

Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma: A Case Report.

作者信息

Tran Dinh Tho, Than Van Sy, Chu Van Vinh, Chu Minh Phuc

机构信息

Department of Hepatobiliary Surgery, Viet Duc University Hospital, Hanoi, VNM.

Department of Radiology, Viet Duc University Hospital, Hanoi, VNM.

出版信息

Cureus. 2025 May 31;17(5):e85147. doi: 10.7759/cureus.85147. eCollection 2025 May.

DOI:10.7759/cureus.85147
PMID:40589681
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12208718/
Abstract

Spinal cord infarction is a rare but serious complication following transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). We report a case of a 33-year-old male with a history of chronic hepatitis B and multiple prior TACE sessions who developed acute paraplegia after undergoing another TACE procedure. With immediate administration of high-dose corticosteroids and supportive care, the patient had partial neurological recovery. This case highlights the importance of recognizing extrahepatic arterial supply and the potential neurological risks associated with TACE.

摘要

脊髓梗死是肝细胞癌(HCC)经动脉化疗栓塞术(TACE)后一种罕见但严重的并发症。我们报告一例33岁男性,有慢性乙型肝炎病史且曾多次接受TACE治疗,在再次接受TACE手术后出现急性截瘫。通过立即给予大剂量皮质类固醇激素和支持治疗,患者神经功能部分恢复。该病例凸显了识别肝外动脉供血以及TACE相关潜在神经风险的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/7f0a41ef25fb/cureus-0017-00000085147-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/fc918d413ad1/cureus-0017-00000085147-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/bcca51fd9b1c/cureus-0017-00000085147-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/f67003addea2/cureus-0017-00000085147-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/7f0a41ef25fb/cureus-0017-00000085147-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/fc918d413ad1/cureus-0017-00000085147-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/bcca51fd9b1c/cureus-0017-00000085147-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/f67003addea2/cureus-0017-00000085147-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/028b/12208718/7f0a41ef25fb/cureus-0017-00000085147-i04.jpg

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本文引用的文献

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Changing etiology and epidemiology of hepatocellular carcinoma: Asia and worldwide.肝细胞癌病因及流行病学的变化:亚洲及全球情况
J Liver Cancer. 2024 Mar;24(1):62-70. doi: 10.17998/jlc.2024.03.13. Epub 2024 Mar 25.
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The progress and controversies regarding steroid use in acute spinal cord injury.类固醇在急性脊髓损伤中的应用的进展和争议。
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Spinal cord ischemia after transcatheter artery chemoembolization for hepatocellular carcinoma: A case-report.
经导管动脉化疗栓塞治疗肝细胞癌后脊髓缺血:一例报告。
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The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
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Overview of Asian clinical practice guidelines for the management of hepatocellular carcinoma: An Asian perspective comparison.亚洲肝细胞癌管理临床实践指南概述:亚洲视角比较。
Clin Mol Hepatol. 2023 Apr;29(2):252-262. doi: 10.3350/cmh.2023.0099. Epub 2023 Mar 10.
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Complications Related to Transarterial Treatment of Hepatocellular Carcinoma: A Comprehensive Review.经动脉治疗肝细胞癌的相关并发症:全面综述。
Korean J Radiol. 2023 Mar;24(3):204-223. doi: 10.3348/kjr.2022.0395. Epub 2023 Jan 19.
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Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma.肝细胞癌经动脉化疗栓塞术后脊髓梗死
Korean J Neurotrauma. 2022 Oct 25;18(2):404-409. doi: 10.13004/kjnt.2022.18.e65. eCollection 2022 Oct.
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Review: Steroid Use in Patients With Acute Spinal Cord Injury and Guideline Update.综述:急性脊髓损伤患者使用类固醇及指南更新
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