Kanfer J N, McCartney D G
Departement of Biochemistry, University of Manitoba, Winnipeg, Canada.
Dev Neurosci. 1989;11(1):26-9. doi: 10.1159/000111882.
The activity of glycerophosphorylcholine phosphodiesterases was determined in the mesencephalon, diencephalon, cerebral hemispheres, cerebellum and olfactory bulb during postnatal development from P5 to P70 of rat brain. These activities are low and gradually increase to near adult levels by the end of the first postnatal month similar to that for CNPase activity. This is in accord with glycerophosphorylcholine choline phosphate phosphodiesterase being present in the myelin membrane.
在大鼠脑从出生后第5天（P5）至第70天（P70）的发育过程中，测定了中脑、间脑、大脑半球、小脑和嗅球中甘油磷酸胆碱磷酸二酯酶的活性。这些活性较低，并在出生后第一个月末逐渐增加至接近成年水平，这与环核苷酸磷酸二酯酶（CNPase）活性的情况相似。这与髓鞘膜中存在甘油磷酸胆碱胆碱磷酸二酯酶相一致。
