Stewart Brian D, Reith John D, Knapik Jacquelyn A, Chi Angela C
Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, USA,
Head Neck Pathol. 2014 Dec;8(4):454-62. doi: 10.1007/s12105-014-0587-8. Epub 2014 Nov 20.
Over the past decade, there have been remarkable advances in bone tumor pathology. Insights into the genetic basis and pathobiology of many tumor types have impacted diagnosis, classification, and treatment. However, because gnathic lesions may comprise only a small proportion of cases overall for many tumors, clinicopathologic features and management considerations specific to this subset may be overlooked. Here we provide a summary of recent developments in the following tumor types: osteosarcoma (OS), chondrosarcoma (CS), osteoid osteoma (OO), osteoblastoma (OB), and Ewing sarcoma (ES). In particular, we will give special consideration to cases arising in the jaws.
在过去十年中,骨肿瘤病理学取得了显著进展。对许多肿瘤类型的遗传基础和病理生物学的深入了解影响了诊断、分类和治疗。然而,由于颌骨病变在许多肿瘤的总体病例中可能只占一小部分,这一亚组特有的临床病理特征和管理考虑因素可能会被忽视。在此,我们总结了以下肿瘤类型的最新进展:骨肉瘤(OS)、软骨肉瘤(CS)、骨样骨瘤(OO)、骨母细胞瘤(OB)和尤因肉瘤(ES)。特别是,我们将特别关注发生于颌骨的病例。