Holshausen Katherine, Bowie Christopher R, Harkness Kate L
a Department of Psychology , Queen's University , Kingston , Ontario , Canada.
b Departments of Psychology & Psychiatry , Queen's University , Kingston , Ontario , Canada.
J Clin Child Adolesc Psychol. 2016;45(3):241-7. doi: 10.1080/15374416.2014.952010. Epub 2014 Nov 20.
This study examined the relation between a history of maltreatment and the presence of psychotic symptoms in a community sample of adolescents and young adults with major depressive disorder. One hundred and twenty-nine depressed adolescents and young adults (M = 16.02 years, 77% female, 92% White) were recruited through community advertisement and clinician referral. Clinical diagnoses and psychotic symptoms (i.e., hallucinations and delusions) were assessed using a structured diagnostic interview. Childhood maltreatment was assessed using a contextual interview and standardized rating system. Logistic regression analyses examined the relation between childhood maltreatment and psychotic symptoms. As hypothesized, individuals with psychotic symptoms were significantly more likely to report a history of severe sexual maltreatment than those without psychotic symptoms (Wald = 5.44, odds ratio = 3.86, p = .020), 95% confidence interval [1.24, 12.01]. Further, those with psychotic symptoms were more likely to report being the victims of more than one type of maltreatment than those without, χ2(2) = 6.66, p = .036 (ϕ = .23; 40% vs. 16%). Results held upon adjusting for overall level of depression symptoms. A history of severe sexual maltreatment is related to a severe presentation of major depressive disorder even in the initial onset of the syndrome in adolescence and young adulthood. These findings underscore the importance of early assessment of both depression and maltreatment history to implement interventions that have the potential to prevent the emergence of psychotic psychopathology in young people at risk.
本研究调查了在患有重度抑郁症的青少年和青年社区样本中,虐待史与精神病症状之间的关系。通过社区广告和临床医生推荐,招募了129名患有抑郁症的青少年和青年(平均年龄M = 16.02岁,77%为女性,92%为白人)。使用结构化诊断访谈评估临床诊断和精神病症状(即幻觉和妄想)。使用情境访谈和标准化评分系统评估儿童期虐待情况。逻辑回归分析检验了儿童期虐待与精神病症状之间的关系。正如所假设的,有精神病症状的个体比没有精神病症状的个体更有可能报告有严重性虐待史(Wald = 5.44,优势比 = 3.86,p = .020),95%置信区间为[1.24, 12.01]。此外,有精神病症状的个体比没有精神病症状的个体更有可能报告遭受过不止一种类型的虐待,χ2(2) = 6.66,p = .036(ϕ = .23;40%对16%)。在对抑郁症状的总体水平进行调整后,结果依然成立。即使在青少年和青年期综合征的初始发作阶段,严重性虐待史也与重度抑郁症的严重表现有关。这些发现强调了早期评估抑郁和虐待史对于实施有可能预防有风险的年轻人出现精神病性精神病理学的干预措施的重要性。