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未经任何细胞毒性治疗的儿童急性淋巴细胞白血病和髓系白血病的短暂缓解:2例报告及文献综述

Transient remission of childhood acute lymphoblastic and myeloid leukemia without any cytostatic treatment: 2 case reports and a review of literature.

作者信息

Pluchart Claire, Munzer Martine, Mauran Pierre, Abély Michel

机构信息

*Unité d'Oncologie Pédiatrique, Service de Pédiatrie A †Service de Pédiatrie A, American Memorial Hospital, CHU Reims, Reims Cedex, France.

出版信息

J Pediatr Hematol Oncol. 2015 Jan;37(1):68-71. doi: 10.1097/MPH.0000000000000152.

DOI:10.1097/MPH.0000000000000152
PMID:25411866
Abstract

Transient remissions (TRs) of acute leukemia without any antileukemic treatment are extremely rare events. We report 2 TRs of acute lymphoblastic leukemia and acute myeloid leukemia in a 2-year-old boy and a 12-year-old girl, respectively, both associated with red blood cells and platelets transfusions and infection. These 2 factors are frequently present in previously reported cases and could induce a stimulation of the immune system although the underlying mechanisms of TRs are still unknown.

摘要

未经任何抗白血病治疗的急性白血病短暂缓解(TRs)是极其罕见的事件。我们分别报告了一名2岁男孩和一名12岁女孩的急性淋巴细胞白血病和急性髓系白血病的2例TRs,两者均与红细胞和血小板输注及感染有关。这两个因素在先前报道的病例中经常出现,尽管TRs的潜在机制尚不清楚,但它们可能会诱导免疫系统的刺激。

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