Webb I J, Anderson K C
Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Semin Oncol. 1997 Feb;24(1):141-6.
Patients with acute myeloid leukemia and acute lymphocytic leukemia receive significant numbers of blood products for hematologic support during periods of disease and treatment related cytopenias. These patients may be at increased risk for complications associated with transfusion. This article reviews the indications for platelet and red blood cell transfusion, as well as the incidence and strategies for prevention of the immunohematologic and infectious sequelae arising in the setting of multiple blood component transfusions.
急性髓系白血病和急性淋巴细胞白血病患者在疾病期及治疗相关血细胞减少期间会接受大量血液制品以获得血液学支持。这些患者发生输血相关并发症的风险可能会增加。本文综述了血小板和红细胞输血的适应证,以及多次输血情况下免疫血液学和感染性后遗症的发生率及预防策略。