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[慢性高血压患者及孕妇的血压昼夜节律]

[Circadian rhythm of blood pressure in patients with chronic hypertension and pregnancy].

作者信息

Rojo-Contreras Wendoline, Salazar-Páramo Mario, Parra-Carrillo José Z, Iñigo-Riesgo Carmen Armida, Bonilla-Rosales Irma, Villa-Manzano Alberto Iram, Canales-Muñoz José Luis

出版信息

Ginecol Obstet Mex. 2014 Sep;82(9):604-12.

PMID:25412554
Abstract

BACKGROUND

Ambulatory blood pressure monitoring during 24 hours shows a blood pressure variability. The prevalence of chronic hypertension in pregnant women is 1-5%, so it is important to know the changes in blood pressure and cardiovascular risk and prevent complications to the mother and fetus.

OBJECTIVE

To know the circadian rhythm of the blood pressure in the chronic hypertensive pregnant patients, through the ambulatory blood pressure monitoring.

MATERIAL AND METHODS

A cross-sectional and descriptive study included chronic hypertensive pregnant patients, with > 20 weeks of gestation. Assessment of factors related to gynaecologic characteristics, according to the inclusion criteria underwent a washout period of two weeks and they were monitored with a Spacelabs 90207 monitor blood pressure. Quantitative variables by Student t test, one-way ANOVA and Pearson correlation were analysed.

RESULTS

16 chronic hypertensive pregnant patients were included, whose ambulatory blood pressure monitoring for the systolic blood pressure in 24 hours averaged 117.12 ± 5.85 mmHg; 24 hours diastolic blood pressure 71.31 ± 5.89 mmHg; daytime systolic blood pressure 120.18 ± 5.75 mmHg, nocturnal systolic blood pressure 110.31 ± 8.41 mmHg; daytime diastolic blood pressure 75.43 ± 7.32 mmHg, nocturnal diastolic blood pressure 64.25 ± 8.27 mmHg. Significant differences between daytime and night time were found.

CONCLUSION

56% of chronic hypertensive pregnant patients had no nocturnal reduction in systolic blood pressure and 43.75% had no nocturnal changes on diastolic blood pressure. The fact that 50% of patients were non-dippers force us to use long-action antihypertensive therapy and obtain control of the blood pressure for 24 hours.

摘要

背景

24小时动态血压监测显示血压存在变异性。孕妇慢性高血压的患病率为1%-5%,因此了解血压变化和心血管风险并预防对母亲和胎儿的并发症很重要。

目的

通过动态血压监测了解慢性高血压孕妇的血压昼夜节律。

材料与方法

一项横断面描述性研究纳入了妊娠>20周的慢性高血压孕妇。根据纳入标准评估与妇科特征相关的因素,经过两周的洗脱期,使用太空实验室90207血压监测仪对她们进行监测。通过学生t检验、单因素方差分析和Pearson相关性分析定量变量。

结果

纳入16例慢性高血压孕妇,其24小时动态血压监测的收缩压平均为117.12±5.85mmHg;24小时舒张压为71.31±5.89mmHg;日间收缩压为120.18±5.75mmHg,夜间收缩压为110.31±8.41mmHg;日间舒张压为75.43±7.32mmHg,夜间舒张压为64.25±8.27mmHg。发现日间和夜间存在显著差异。

结论

56%的慢性高血压孕妇夜间收缩压无下降,43.75%的孕妇夜间舒张压无变化。50%的患者为非勺型血压这一事实迫使我们使用长效抗高血压治疗并实现24小时血压控制。

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[Circadian rhythm of blood pressure in patients with chronic hypertension and pregnancy].[慢性高血压患者及孕妇的血压昼夜节律]
Ginecol Obstet Mex. 2014 Sep;82(9):604-12.
2
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G Ital Cardiol. 1998 Jan;28(1):38-44.
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[Circadian blood pressure variation in normal pregnancy, gestational hypertension, and preeclampsia].[正常妊娠、妊娠期高血压和子痫前期的昼夜血压变化]
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Curr Hypertens Rep. 2020 Jul 15;22(8):53. doi: 10.1007/s11906-020-01066-w.
2
Ambulatory blood pressure monitoring over 24 h: A Latin American Society of Hypertension position paper-accessibility, clinical use and cost effectiveness of ABPM in Latin America in year 2020.24 小时动态血压监测:拉丁美洲高血压学会立场文件——2020 年拉丁美洲动态血压监测的可及性、临床应用和成本效益。
J Clin Hypertens (Greenwich). 2020 Apr;22(4):527-543. doi: 10.1111/jch.13816. Epub 2020 Feb 12.