Basic David, Shanley Chris
University of New South Wales, Australia
University of New South Wales, Australia.
J Aging Health. 2015 Jun;27(4):670-85. doi: 10.1177/0898264314558202. Epub 2014 Nov 19.
To evaluate the impact of frailty, measured using the Canadian Study of Health and Aging Clinical Frailty Scale, on outcomes of older people hospitalized with acute illness.
Consecutive patients were randomly allocated to a model development sample or a model validation sample. Multivariate analyses were used to model in-hospital mortality, new nursing home placement, and length of stay. Variables selected in the development samples were tested in the validation samples.
The mean age of all 2,125 patients was 82.9 years. Most (93.6%) were admitted through the emergency department. Frailty predicted in-hospital mortality (odds ratio [OR] = 2.97 [2.11, 4.17]), new nursing home placement (OR = 1.60 [1.14, 2.24]), and length of hospital stay (hazard ratio = 0.87 [0.81, 0.93]).
Frailty is a strong predictor of adverse outcomes in older people hospitalized with acute illness. An increased awareness of its impact may alert clinicians to screen for frailty.
使用加拿大健康与老龄化临床衰弱量表来评估衰弱对急性病住院老年人预后的影响。
将连续的患者随机分配到模型开发样本或模型验证样本中。采用多变量分析来建立住院死亡率、新入住养老院情况和住院时间的模型。在开发样本中选择的变量在验证样本中进行测试。
2125例患者的平均年龄为82.9岁。大多数(93.6%)是通过急诊科入院的。衰弱可预测住院死亡率(比值比[OR]=2.97[2.11,4.17])、新入住养老院情况(OR=1.60[1.14,2.24])和住院时间(风险比=0.87[0.81,0.93])。
衰弱是急性病住院老年人不良预后的有力预测指标。提高对其影响的认识可能会提醒临床医生对衰弱进行筛查。