Ferris Helena A, Walsh Mary E, Merriman Niamh A, Brent Louise, Hickey Pamela, Regan Niamh O ', Coughlan Tara, Romero-Ortuno Roman
Department of Public Health, Health Service Executive - South West, St. Finbarr's Hospital, Cork, Ireland.
School of Pharmacy and Biomolecular Science, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland.
Eur Geriatr Med. 2025 Jul 2. doi: 10.1007/s41999-025-01268-y.
Frail older adults are at increased risk of adverse outcomes after hip fracture. We compared the Clinical Frailty Scale (CFS) and the Irish Hip Fracture Database Frailty Index (IHFD FI) in predicting hospital outcomes.
A secondary analysis of national clinical audit data from two trauma units was conducted. The CFS and IHFD FI were derived from routinely collected data. Multivariable logistic regression assessed the predictive value of age, sex, ASA grade, plus either frailty tool for the following outcomes: delirium (positive 4AT and/or clinical diagnosis), inpatient mortality, prolonged length of stay (LOS ≥ 30 days) and discharge home within 14 days. Predictive performance was evaluated using area under the curve (AUC).
The study included 1,388 patients discharged between 1st January 2022 and 31st December 2023 (mean age 80.0, 68.4% female). Delirium occurred in 39.1%, inpatient mortality in 5.2%, prolonged LOS in 22.2% and 33.6% were discharged home within 14 days. CFS data were available for 84.4% and IHFD FI for 86.5%. When added to age, sex and ASA, the CFS outperformed the IHFD FI for predicting delirium (AUC 0.816 vs. 0.790), while the IHFD FI was better for mortality (AUC 0.778 vs. 0.744). Both tools performed similarly for prolonged LOS and discharge home.
Both the CFS and IHFD FI were predictive of outcomes. However, the CFS demonstrated superior predictive value for delirium during admission. Prospective collection of the CFS is recommended to enhance the identification of patients at risk of delirium and to support timely clinical interventions.
体弱的老年人髋部骨折后出现不良后果的风险增加。我们比较了临床衰弱量表(CFS)和爱尔兰髋部骨折数据库衰弱指数(IHFD FI)对医院结局的预测能力。
对来自两个创伤单元的全国临床审计数据进行二次分析。CFS和IHFD FI源自常规收集的数据。多变量逻辑回归评估年龄、性别、美国麻醉医师协会(ASA)分级以及两种衰弱工具之一对以下结局的预测价值:谵妄(4AT阳性和/或临床诊断)、住院死亡率、住院时间延长(住院时间≥30天)以及14天内出院回家。使用曲线下面积(AUC)评估预测性能。
该研究纳入了2022年1月1日至2023年12月31日期间出院的1388例患者(平均年龄80.0岁,68.4%为女性)。谵妄发生率为39.1%,住院死亡率为5.2%,住院时间延长的比例为22.2%,33.6%的患者在14天内出院回家。84.4%的患者有CFS数据,86.5%的患者有IHFD FI数据。在年龄、性别和ASA分级基础上,CFS在预测谵妄方面优于IHFD FI(AUC为0.816对0.790),而IHFD FI在预测死亡率方面表现更好(AUC为0.778对0.744)。两种工具在预测住院时间延长和出院回家方面表现相似。
CFS和IHFD FI都能预测结局。然而,CFS在入院期间谵妄的预测方面具有更高的预测价值。建议前瞻性收集CFS以加强对有谵妄风险患者的识别,并支持及时的临床干预。