维持性血液透析老年患者中衰弱的患病率：一项系统性研究。（你提供的原文似乎不完整，推测这可能是标题之类的内容）

The prevalence of frailty among older adults with maintenance hemodialysis: a systematic.

作者信息

Li Juanjuan, Xiao Wenyi, Wang Lijuan, Zhang Miao, Ge Yurong

机构信息

College of Nursing, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.

Department of Medical Education, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia, 750002, China.

出版信息

BMC Nephrol. 2025 Jan 7;26(1):10. doi: 10.1186/s12882-024-03921-3.

DOI:10.1186/s12882-024-03921-3

PMID:39794749

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11724589/

Abstract

BACKGROUND

To evaluate the epidemiological data on the prevalence of frailty and prefrailty in individuals aged 60 years or older on MHD patients.

METHODS

PubMed, Web of Science, Embase, CNKI, WanFang, CBM, and VIP were searched from inception to February 2023 using combinations of subject words and free words. The methodological quality of all the selected studies was assessed using the Joanna Briggs Institute Critical Appraisal of Epidemiological Studies Checklist and Newcastle‒Ottawa Cohort Quality Assessment Scale. Random effects meta-analysis was used to pool estimates from different studies. Subgroup analysis and meta-regression were performed to explore potential sources of heterogeneity.

RESULTS

Of the 4,190 documents retrieved, 16 observational studies involving 2,446 participants from 8 countries were included in this systematic review. Among older adults receiving MHD, the overall prevalence of frailty and prefrailty was 41% (95% CI = 34-49%) and 37% (95% CI = 26-48%), respectively, with considerable heterogeneity. The pooled prevalence of frailty was greater among individuals aged > 70 years (45%) than among those aged ≤ 70 years (37%). However, subgroup analyses indicated that the confidence intervals for the age group overlap substantially.

CONCLUSION

Our research showed that the prevalence of frailty and prefrailty in older patients with MHD are high.

TRIAL REGISTRATION

The PROSPERO registration number for this study was CRD42023442569.

摘要

背景

评估维持性血液透析（MHD）患者中60岁及以上个体的衰弱和衰弱前期患病率的流行病学数据。

方法

从创刊至2023年2月，使用主题词和自由词组合在PubMed、科学网、Embase、中国知网、万方、中国生物医学文献数据库和维普资讯网进行检索。使用乔安娜·布里格斯研究所流行病学研究批判性评价清单和纽卡斯尔-渥太华队列质量评估量表评估所有入选研究的方法学质量。采用随机效应荟萃分析汇总不同研究的估计值。进行亚组分析和荟萃回归以探索异质性的潜在来源。

结果

在检索到的4190篇文献中，本系统评价纳入了16项观察性研究，涉及来自8个国家的2446名参与者。在接受MHD的老年人中，衰弱和衰弱前期的总体患病率分别为41%（95%CI=34-49%）和37%（95%CI=26-48%），存在相当大的异质性。年龄>70岁的个体中衰弱的合并患病率（45%）高于年龄≤70岁的个体（37%）。然而亚组分析表明，该年龄组的置信区间有很大重叠。