Adib-Hajbaghery Mohsen, Mahmoudi Mansoreh, Mashaiekhi Mahdi
Trauma Nursing Research Center, Kashan University of Medical Sciences, Kashan, IR Iran.
Department of Medical-Surgical Nursing, Faculty of Nursing and Midwifery, Arak University of Medical Sciences, Arak, IR. Iran.
Nurs Midwifery Stud. 2014 Jun;3(2):e14180. Epub 2014 Jun 15.
Diaper rash is one of the most common skin disorders of infancy and childhood. Some studies have shown that Shampoo-clay was effective to treat chronic dermatitis. Then, it is supposed that it may be effective in diaper rash; however, no published studies were found in this regard.
This study aimed to compare the effects of Shampoo-clay (S.C) and Calendula officinalis (C.O) to improve infantile diaper rash.
A randomized, double blind, parallel controlled, non-inferiority trial was conducted on 60 outpatient infants referred to health care centers or pediatric clinics in Khomein city and diagnosed with diaper rash. Patients were randomly assigned into two treatment groups including S.C group (n = 30) and C.O group (n = 30) by using one to one allocation ratio. The rate of complete recovery in three days was the primary outcome. Data was collected using a checklist and analyzed using t-test, Chi-square and Fisher's exact tests and risk ratio.
Totally, 93.3% of lesions in the S.C group healed in the first 6 hours, while this rate was 40% in C.O group (P < 0.001). The healing ratio for improvement in the first 6 hours was 7 times more in the S.C group. In addition, 90% of infants in the SC group and 36.7% in the C.O group were improved completely in the first 3 days (P < 0.001).
S.C was effective to heal diaper rash, and also had faster effects compared to C.O.
尿布疹是婴幼儿时期最常见的皮肤疾病之一。一些研究表明,洗发用黏土对治疗慢性皮炎有效。因此,推测其可能对尿布疹也有效;然而,尚未发现这方面的已发表研究。
本研究旨在比较洗发用黏土(S.C)和金盏花(C.O)改善婴儿尿布疹的效果。
对60名转诊至霍梅因市医疗保健中心或儿科诊所且被诊断为尿布疹的门诊婴儿进行了一项随机、双盲、平行对照、非劣效性试验。采用一对一分配比例将患者随机分为两个治疗组,即S.C组(n = 30)和C.O组(n = 30)。三天内的完全恢复率为主要结局。使用检查表收集数据,并采用t检验、卡方检验、费舍尔精确检验和风险比进行分析。
总体而言,S.C组93.3%的皮损在最初6小时内愈合,而C.O组的这一比例为40%(P < 0.001)。S.C组在最初6小时内改善的愈合率是C.O组的7倍。此外,S.C组90%的婴儿和C.O组36.7%的婴儿在最初3天内完全改善(P < 0.001)。
S.C对治愈尿布疹有效,且与C.O相比起效更快。