Chen Run-Zhe, Zhao Gang, Jin Nan, Chen Bao-An, Ding Jia-Hua
Department of Hematology and Oncology, Key Department of Jiangsu Medicine, Zhongda Hospital, Medical School, Southeast University, Nanjing, Jiangsu Province, People's Republic of China.
Patient Prefer Adherence. 2014 Nov 13;8:1581-5. doi: 10.2147/PPA.S72875. eCollection 2014.
Superselective arterial embolization is a common therapeutic procedure for cases of visceral hemorrhage. However, until now, it has not been applied in the treatment of gastrointestinal (GI) hemorrhage caused by acute graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation. We describe a case presenting with persistent GI bleeding associated with acute GVHD successfully treated by superselective arterial embolization of the superior mesenteric artery with gelatin sponge after noneffective conventional management. This case will help guide hematologists to deal with a similar situation in the future.
超选择性动脉栓塞是治疗内脏出血的常见治疗方法。然而,迄今为止,它尚未应用于异基因造血干细胞移植后急性移植物抗宿主病(GVHD)所致的胃肠道(GI)出血的治疗。我们描述了1例在常规治疗无效后,通过用明胶海绵对肠系膜上动脉进行超选择性动脉栓塞成功治疗的、伴有急性GVHD的持续性GI出血病例。该病例将有助于指导血液科医生在未来处理类似情况。