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输卵管妊娠保守治疗后通过腹腔镜和宫腔镜进行不孕症评估。

Infertility evaluation via laparoscopy and hysteroscopy after conservative treatment for tubal pregnancy.

作者信息

Hu Chunxiu, Chen Ziru, Hou Haiyan, Xiao Chen, Kong Xiangling, Chen Yaqiong

机构信息

Department of Obstetrics & Gynecology, Affiliated Hospital of The Chinese People's Armed, Police Force Logistics College Tianjin, China.

出版信息

Int J Clin Exp Med. 2014 Oct 15;7(10):3556-61. eCollection 2014.

Abstract

OBJECTIVE

Evaluate the cause of infertility and impairment of tubal reproductive functions in infertility patients, who suffered tubal pregnancy after conservative treatment, using laparoscopy, hysteroscopic tubal catheterization, and hydrotubation.

METHODS

Seventy-five infertility patients treated for tubal pregnancies were divided into two groups based on past treatment methods of their tubal pregnancies, conservative-medical group and conservative-surgical group. The severity of pelvic adhesions, tubal morphology, tubal fimbria, and other infertility factors were observed via laparoscopy. Additionally, hysteroscopic tubal catheterization and hydrotubation was used to diagnose tubal patency and evaluate the intrauterine cavity.

RESULTS

There were one or more factors associated with infertility in the 75 patients, among which abnormal tubal was an absolutely important factor. In conservative-medical group, 92.11% (35/38) of the patients were with bilateral or unilateral oviduct exceptions, such as adhesion around or distorted tubal, closure or adhesion in umbrella end, lumen block. In conservative-surgical group, all of the patients were with bilateral or unilateral fallopian tube lesions. As two fallopian tubes per patient, 80.26% (61/76) of the tubes in conservative-medical group was damaged, 95.95% (71/74) in conservative-surgical group. The differences between the two groups was significant (P < 0.05). However, differences between these two groups in morphology of damaged tubes, anomaly of umbrella end and occlusion of lumen were not significant (P > 0.05). Incidence of pelvic adhesions in conservative-medical group was 76.32% (29/38), which was lower than 100% (37/37) of conservative-surgical group. The difference was significant (P < 0.05), which suggested that conservative-medical treatment was more effective than surgical treatment in preventing pelvic adhesion.

CONCLUSION

Factors associated with tubal infertility affect patients who accepted conservative treatment for tubal pregnancy. In patients with a history of a tubal pregnancy, it may be less likely to compromise future reproductive function for conservative-medical treated patients than that for conservative-surgery treated patients.

摘要

目的

采用腹腔镜、宫腔镜输卵管插管及输卵管通液术,评估保守治疗后发生输卵管妊娠的不孕症患者的不孕原因及输卵管生殖功能损害情况。

方法

将75例接受输卵管妊娠治疗的不孕症患者,根据既往输卵管妊娠的治疗方法分为两组,即保守药物组和保守手术组。通过腹腔镜观察盆腔粘连的严重程度、输卵管形态、输卵管伞端及其他不孕因素。此外,采用宫腔镜输卵管插管及输卵管通液术诊断输卵管通畅情况并评估宫腔情况。

结果

75例患者中存在一个或多个与不孕相关的因素,其中输卵管异常是绝对重要的因素。保守药物组中,92.11%(35/38)的患者存在双侧或单侧输卵管异常,如输卵管周围粘连或扭曲、伞端闭锁或粘连、管腔阻塞。保守手术组中,所有患者均存在双侧或单侧输卵管病变。以每位患者两条输卵管计算,保守药物组80.26%(61/76)的输卵管受损,保守手术组为95.95%(71/74)。两组间差异有统计学意义(P<0.05)。然而,两组在受损输卵管形态、伞端异常及管腔阻塞方面的差异无统计学意义(P>0.05)。保守药物组盆腔粘连发生率为76.32%(29/38),低于保守手术组的100%(37/37)。差异有统计学意义(P<0.05),提示保守药物治疗在预防盆腔粘连方面比手术治疗更有效。

结论

与输卵管不孕相关的因素影响接受输卵管妊娠保守治疗的患者。有输卵管妊娠病史的患者,保守药物治疗患者未来生殖功能受损的可能性可能低于保守手术治疗患者。

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本文引用的文献

1
Fertility after ectopic pregnancy: the DEMETER randomized trial.宫外孕后生育能力:DEMETER 随机试验。
Hum Reprod. 2013 May;28(5):1247-53. doi: 10.1093/humrep/det037. Epub 2013 Mar 12.
2
Ectopic pregnancy rates in the Medicaid population. Medicaid 人群中的宫外孕发生率。
Am J Obstet Gynecol. 2013 Apr;208(4):274.e1-7. doi: 10.1016/j.ajog.2012.12.038. Epub 2013 Jan 8.
4
Fertility after tubal ectopic pregnancy: results of a population-based study.输卵管妊娠后生育力:一项基于人群的研究结果。
Fertil Steril. 2012 Nov;98(5):1271-6.e1-3. doi: 10.1016/j.fertnstert.2012.06.041. Epub 2012 Jul 18.
5
Laparoscopic management of ectopic pregnancy during a 9-year period.9 年期间腹腔镜处理宫外孕的临床分析。
Fertil Steril. 2010 Dec;94(7):2780-2. doi: 10.1016/j.fertnstert.2010.04.051. Epub 2010 Jun 3.
7
Ectopic pregnancy in adolescents.青少年异位妊娠
Curr Opin Obstet Gynecol. 2008 Oct;20(5):475-8. doi: 10.1097/GCO.0b013e32830d0ce1.
8
Evidence-based diagnosis and management of tubal factor infertility.
Curr Opin Obstet Gynecol. 2004 Jun;16(3):221-9. doi: 10.1097/00001703-200406000-00004.
9
Increased infertility with age in men and women.男性和女性的不孕率随年龄增长而上升。
Obstet Gynecol. 2004 Jan;103(1):51-6. doi: 10.1097/01.AOG.0000100153.24061.45.

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