Sartelli Massimo, Malangoni Mark A, May Addison K, Viale Pierluigi, Kao Lillian S, Catena Fausto, Ansaloni Luca, Moore Ernest E, Moore Fred A, Peitzman Andrew B, Coimbra Raul, Leppaniemi Ari, Kluger Yoram, Biffl Walter, Koike Kaoru, Girardis Massimo, Ordonez Carlos A, Tavola Mario, Cainzos Miguel, Di Saverio Salomone, Fraga Gustavo P, Gerych Igor, Kelly Michael D, Taviloglu Korhan, Wani Imtiaz, Marwah Sanjay, Bala Miklosh, Ghnnam Wagih, Shaikh Nissar, Chiara Osvaldo, Faro Mario Paulo, Pereira Gerson Alves, Gomes Carlos Augusto, Coccolini Federico, Tranà Cristian, Corbella Davide, Brambillasca Pietro, Cui Yunfeng, Segovia Lohse Helmut A, Khokha Vladimir, Kok Kenneth Yy, Hong Suk-Kyung, Yuan Kuo-Ching
Department of Surgery, Macerata Hospital, Via Santa Lucia 2, Macerata, 62019 Italy.
American Board of Surgery, Philadelphia, USA.
World J Emerg Surg. 2014 Nov 18;9(1):57. doi: 10.1186/1749-7922-9-57. eCollection 2014.
Skin and soft tissue infections (SSTIs) encompass a variety of pathological conditions ranging from simple superficial infections to severe necrotizing soft tissue infections. Necrotizing soft tissue infections (NSTIs) are potentially life-threatening infections of any layer of the soft tissue compartment associated with widespread necrosis and systemic toxicity. Successful management of NSTIs involves prompt recognition, timely surgical debridement or drainage, resuscitation and appropriate antibiotic therapy. A worldwide international panel of experts developed evidence-based guidelines for management of soft tissue infections. The multifaceted nature of these infections has led to a collaboration among surgeons, intensive care and infectious diseases specialists, who have shared these guidelines, implementing clinical practice recommendations.
皮肤和软组织感染（SSTIs）涵盖了从简单的浅表感染到严重的坏死性软组织感染等多种病理状况。坏死性软组织感染（NSTIs）是软组织间隙任何一层潜在危及生命的感染，伴有广泛坏死和全身毒性。NSTIs的成功治疗包括迅速识别、及时手术清创或引流、复苏以及适当的抗生素治疗。一个国际专家小组制定了基于证据的软组织感染管理指南。这些感染的多方面性质促使外科医生、重症监护和传染病专家之间展开合作，他们分享了这些指南，并实施临床实践建议。
