1型糖尿病患儿唾液甘油三酯和胆固醇与龋齿的关联

Association of salivary triglycerides and cholesterol with dental caries in children with type 1 diabetes mellitus.

作者信息

Subramaniam Priya, Sharma Akhliesh, Kaje Keerthan

机构信息

Principal, Professor and Head, Department of Pedodontics and Preventive Dentistry, The Oxford Dental College and Hospital, Bangalore, India.

出版信息

Spec Care Dentist. 2015 May-Jun;35(3):120-2. doi: 10.1111/scd.12097. Epub 2014 Nov 26.

DOI:10.1111/scd.12097

PMID:25423954

Abstract

BACKGROUND

Metabolic disturbances in diabetes mellitus can affect oral health. Altered levels of salivary lipids have been suggested as a risk for dental caries. There has been lack of research in this regard and in children with type 1 diabetes mellitus.

AIM

To assess the salivary triglycerides and cholesterol levels in children with type 1 diabetes mellitus and correlate them with their dental caries status.

MATERIALS AND METHODS

Thirty children aged 12-16 years with type 1 diabetes mellitus and 30 age- and gender-matched healthy children were included in the study. Unstimulated saliva was collected from each child and evaluated for salivary triglyceride and cholesterol levels. Dental caries status (DMFT) was recorded.

RESULTS

Salivary cholesterol and triglyceride levels were significantly higher in children with type 1 diabetes mellitus (p ≤ 0.05). In comparison to controls, mean DMFT score was higher in the diabetic children. Salivary triglycerides showed a significant correlation with dental caries status in the study group (p = 0.035). In normal children, salivary cholesterol levels showed a significant association with dental caries. (p = 0.008).

CONCLUSION

Both salivary cholesterol and triglycerides levels were significantly higher in children with type 1 diabetes mellitus. Salivary triglycerides showed a significant association with dental caries in these children.

摘要