Umbreit M H
Pol J Pharmacol Pharm. 1978 Jan-Feb;30(1):119-23.
Aluminium phosphate was precipitated from AlCl3-H3PO4 and NaOH, NH3H2O and NaHCO3--Na2CO3 mixture up to different pH values. The precipitates were dried at room temperature, 40 degrees and 105 degrees and their neutralizing properties (rate of neutralization and acid-consuming capacity) against 0.l N HCl were investigated. It was found that these properties depend on the nature of the reagents used for the formation of AlPO4, the pH and also the temperature of drying. The best antacid properties shows the AlPO4 preperation obtained from AlCl3-H3PO4 and NaHCO3-Na2CO3. For comparison, the therapeutic preparate "Aluphos" was also investigated.
磷酸铝是由氯化铝 - 磷酸、氢氧化钠、氨水和碳酸氢钠 - 碳酸钠混合物在不同pH值下沉淀得到的。沉淀物在室温、40摄氏度和105摄氏度下干燥，并研究了它们对0.1N盐酸的中和性能（中和速率和耗酸能力）。发现这些性能取决于用于形成磷酸铝的试剂的性质、pH值以及干燥温度。由氯化铝 - 磷酸和碳酸氢钠 - 碳酸钠制得的磷酸铝制剂具有最佳的抗酸性能。为作比较，还对治疗制剂“Aluphos”进行了研究。
