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胃酸过多治疗用药的制备。第一部分。沉淀pH值对氧化铝凝胶中和性能的影响。

Preparation of drugs used in hyperacidity. Part I. Effects of pH of precipitation on the neutralizing properties of alumina gels.

作者信息

Pawlaczyk J, Kokot Z, Zuzak A

出版信息

Pol J Pharmacol Pharm. 1976 Jan-Feb;28(1):55-60.

PMID:4777
Abstract

Alumina gels were obtained from sodium aluminate by addition of 3 N HNO3, HCl or H2SO4 solutions or by saturation with gaseous CO2. The effect of several physicochemical factors (pH of precipitation, kind and concentration of precipitating agent, temperature) on the neutralizing properties of the obtained forms of Al(OH)3 was investigated. The linear correlation between the pH of precipitation and the neutralizing properties was found. The effect of different precipitating anions on the acid-consuming capacity and the rate of neutralization of 0-1 N HCl was established.

摘要

通过添加3N硝酸、盐酸或硫酸溶液或用气态二氧化碳饱和从铝酸钠中获得氧化铝凝胶。研究了几个物理化学因素(沉淀pH值、沉淀剂种类和浓度、温度)对所得氢氧化铝形式的中和性能的影响。发现沉淀pH值与中和性能之间存在线性相关性。确定了不同沉淀阴离子对0-1N盐酸的耗酸能力和中和速率的影响。

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