de Almeida Lopes Ana Carolina Bertin, Navas-Acien Ana, Zamoiski Rachel, Silbergeld Ellen Kovner, Carvalho Maria de Fatima H, Buzzo Marcia Liane, Urbano Mariana Ragassi, Martins Airton da Cunha, Paoliello Monica Maria Bastos
a Graduate Program in Public Health, Center of Health Sciences , State University of Londrina , Parana , Brazil.
J Toxicol Environ Health A. 2015;78(2):92-108. doi: 10.1080/15287394.2014.942125.
In Brazil there is no systematic evaluation to access blood lead levels (BLL) in the general population and few studies with adults have been published. The aim of this study was to examine the socioeconomic, environmental, and lifestyle determinants of BLL in the adult Brazilian population. In total, 959 adults, aged 40 years or more, were randomly selected in a city in southern Brazil. Information on socioeconomic, dietary, lifestyle, and occupational background was obtained by interviews. A spatial analysis was conducted to discern whether there were any identifiable sources of exposure. BLL were measured by inductively coupled plasma-mass spectrometry. There was an adjustment for gender, age, race, education, income class, smoking status, alcohol consumption, occupation, and red meat or cow milk consumption (Model 1), and for occupation and gender (Model 2). The geometric mean of BLL was 1.97 μg/dl (95% CI: 1.9-2.04 μg/dl). In Model 1, BLL were positively associated with male gender, older age, and drinking and smoking habits, and less frequently with milk consumption. In Model 2, data showed higher BLL in non-white than white participants, in former smokers and individuals with current or former employment in lead (Pb) industries. The participants living in the area with more Pb industries had higher BLL (3.3 μg/dl) compared with those residing in other areas with no or fewer Pb industries (1.95 μg/dl). Despite the low BLL found in adults living in an urban area, Pb industries need to be monitored and regulatory laws implemented to prevent metal contamination in urban settings.
在巴西,没有对普通人群血铅水平(BLL)进行系统评估,且针对成年人的相关研究发表较少。本研究旨在探讨巴西成年人群中BLL的社会经济、环境和生活方式决定因素。总共在巴西南部一个城市随机选取了959名40岁及以上的成年人。通过访谈获取了有关社会经济、饮食、生活方式和职业背景的信息。进行了空间分析以识别是否存在任何可确定的暴露源。通过电感耦合等离子体质谱法测量BLL。对性别、年龄、种族、教育程度、收入阶层、吸烟状况、饮酒量、职业以及红肉或牛奶摄入量进行了调整(模型1),并对职业和性别进行了调整(模型2)。BLL的几何平均值为1.97μg/dl(95%置信区间:1.9 - 2.04μg/dl)。在模型1中,BLL与男性性别、年龄较大以及饮酒和吸烟习惯呈正相关,与牛奶摄入量的相关性较低。在模型2中,数据显示非白人参与者、既往吸烟者以及目前或曾经在铅(Pb)行业工作的个体的BLL较高。与居住在其他没有或铅行业较少地区的参与者(1.95μg/dl)相比,居住在铅行业较多地区的参与者BLL更高(3.3μg/dl)。尽管在城市地区成年人中发现的BLL较低,但仍需对铅行业进行监测并实施监管法律,以防止城市环境中的金属污染。