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Discov Oncol. 2025 Jul 30;16(1):1444. doi: 10.1007/s12672-025-03284-7.
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BRAF p.V600E Mutational Status Does Not Correlate with Biological Behavior in Conventional Ameloblastomas: A Disease-Free Survival Analysis.BRAF p.V600E 突变状态与常规成釉细胞瘤的生物学行为无关：无病生存分析。
Head Neck Pathol. 2024 Mar 19;18(1):23. doi: 10.1007/s12105-024-01621-w.
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Comparison of diagnostic methods for detection of BRAFV600E mutation in ameloblastoma.成釉细胞瘤 BRAFV600E 突变检测方法的比较。
J Oral Pathol Med. 2024 Jan;53(1):79-87. doi: 10.1111/jop.13506. Epub 2024 Jan 7.
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Three-dimensional printed titanium mesh combined with iliac cancellous bone in the reconstruction of mandibular defects secondary to ameloblastoma resection.三维打印钛网联合髂骨松质骨重建造釉细胞瘤术后下颌骨缺损
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Machine learning-based radiomics for predicting BRAF-V600E mutations in ameloblastoma.基于机器学习的影像组学预测造釉细胞瘤中 BRAF-V600E 突变。
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V600E Mutation in Ameloblastoma: A Systematic Review and Meta-Analysis.成釉细胞瘤中的V600E突变：一项系统评价和荟萃分析。
Cancers (Basel). 2022 Nov 14;14(22):5593. doi: 10.3390/cancers14225593.
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Inhibition of L-type voltage-gated calcium channel-mediated Ca influx suppresses the collective migration and invasion of ameloblastoma.抑制 L 型电压门控钙通道介导的 Ca 内流可抑制成釉细胞瘤的集体迁移和侵袭。
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本文引用的文献

1
Early dental epithelial transcription factors distinguish ameloblastoma from keratocystic odontogenic tumor.早期牙上皮转录因子可区分成釉细胞瘤与牙源性角化囊性瘤。
J Dent Res. 2015 Jan;94(1):101-11. doi: 10.1177/0022034514556815. Epub 2014 Nov 14.
2
Systemic treatment for BRAF-mutant melanoma: where do we go next?BRAF 突变型黑色素瘤的系统性治疗：下一步我们该何去何从？
Lancet Oncol. 2014 Aug;15(9):e371-81. doi: 10.1016/S1470-2045(14)70072-5.
3
Activating FGFR2-RAS-BRAF mutations in ameloblastoma.在造釉细胞瘤中激活 FGFR2-RAS-BRAF 突变。
Clin Cancer Res. 2014 Nov 1;20(21):5517-26. doi: 10.1158/1078-0432.CCR-14-1069. Epub 2014 Jul 3.
4
Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond.靶向RAF激酶用于癌症治疗：BRAF突变型黑色素瘤及其他情况。
Nat Rev Cancer. 2014 Jul;14(7):455-67. doi: 10.1038/nrc3760.
5
Identification of recurrent SMO and BRAF mutations in ameloblastomas.成釉细胞瘤中复发性SMO和BRAF突变的鉴定。
Nat Genet. 2014 Jul;46(7):722-5. doi: 10.1038/ng.2986. Epub 2014 May 25.
6
Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma.开放性、探索性 II 期临床试验：口服伊曲康唑治疗基底细胞癌。
J Clin Oncol. 2014 Mar 10;32(8):745-51. doi: 10.1200/JCO.2013.49.9525. Epub 2014 Feb 3.
7
High frequency of BRAF V600E mutations in ameloblastoma.成釉细胞瘤中 BRAF V600E 突变的高频性。
J Pathol. 2014 Apr;232(5):492-8. doi: 10.1002/path.4317. Epub 2014 Jan 31.
8
MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study.MEK162 治疗携带 NRAS 或 Val600 BRAF 突变的晚期黑色素瘤患者：一项非随机、开放标签的 2 期研究。
Lancet Oncol. 2013 Mar;14(3):249-56. doi: 10.1016/S1470-2045(13)70024-X. Epub 2013 Feb 13.
9
Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists.伊曲康唑和三氧化二砷抑制 Hedgehog 通路的激活和获得性对 smoothened 拮抗剂耐药相关的肿瘤生长。
Cancer Cell. 2013 Jan 14;23(1):23-34. doi: 10.1016/j.ccr.2012.11.017. Epub 2013 Jan 3.
10
FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features.466 例子宫内膜样肿瘤中 FGFR2 点突变：与 MSI、KRAS、PIK3CA、CTNNB1 突变及临床病理特征的关系。
PLoS One. 2012;7(2):e30801. doi: 10.1371/journal.pone.0030801. Epub 2012 Feb 23.

Novel targets for the treatment of ameloblastoma.

作者信息

Heikinheimo K, Kurppa K J, Elenius K

机构信息

Department of Oral and Maxillofacial Surgery, Institute of Dentistry, University of Turku, Turku, Finland Turku University Hospital, Turku, Finland Department of Oral Diagnostic Sciences, Institute of Dentistry, University of Eastern Finland, Kuopio, Finland Department of Oral and Maxillofacial Diseases, Kuopio University Hospital, Kuopio, Finland

Department of Medical Biochemistry and Genetics, University of Turku, Turku, Finland MediCity Research Laboratories, University of Turku, Turku, Finland Turku Doctoral Programme of Molecular Medicine, Turku, Finland.

出版信息

J Dent Res. 2015 Feb;94(2):237-40. doi: 10.1177/0022034514560373. Epub 2014 Nov 25.

DOI:10.1177/0022034514560373
PMID:25425580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4438731/
Abstract
摘要