• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

早发型新生儿败血症：诊断难题与实际管理

Early onset neonatal sepsis: diagnostic dilemmas and practical management.

作者信息

Bedford Russell A R, Kumar R

机构信息

Neonatal Unit, Birmingham Women's NICU, Birmingham, UK.

出版信息

Arch Dis Child Fetal Neonatal Ed. 2015 Jul;100(4):F350-4. doi: 10.1136/archdischild-2014-306193. Epub 2014 Nov 25.

DOI:10.1136/archdischild-2014-306193
PMID:25425652
Abstract

Early onset neonatal sepsis is persistently associated with poor outcomes, and incites clinical practice based on the fear of missing a treatable infection in a timely fashion. Unnecessary exposure to antibiotics is also hazardous. Diagnostic dilemmas are discussed in this review, and suggestions offered for practical management while awaiting a more rapidly available 'gold standard' test; in an ideal world, this test would be 100% sensitive and 100% specific for the presence of organisms.

摘要

早发型新生儿败血症一直与不良预后相关，并且基于对未能及时发现可治疗感染的担忧而引发临床实践。不必要地使用抗生素也有危害。本综述讨论了诊断难题，并针对等待更快速可用的“金标准”检测期间的实际管理提供了建议；在理想情况下，该检测对于病原体的存在应具有100%的敏感性和100%的特异性。

相似文献

1
Early onset neonatal sepsis: diagnostic dilemmas and practical management.早发型新生儿败血症：诊断难题与实际管理
Arch Dis Child Fetal Neonatal Ed. 2015 Jul;100(4):F350-4. doi: 10.1136/archdischild-2014-306193. Epub 2014 Nov 25.
2
Clinical microbiology of early-onset and late-onset neonatal sepsis, particularly among preterm babies.早发型和晚发型新生儿败血症的临床微生物学，尤其是在早产儿中。
Acta Microbiol Immunol Hung. 2009 Mar;56(1):21-51. doi: 10.1556/AMicr.56.2009.1.2.
3
Sepsis in the neonate.新生儿脓毒症
Crit Care Nurs Clin North Am. 2009 Mar;21(1):121-41, vii. doi: 10.1016/j.ccell.2008.11.002.
4
Neonatal sepsis.新生儿败血症。
Biochem Med (Zagreb). 2011;21(3):276-81. doi: 10.11613/bm.2011.037.
5
Quality in practice: preventing and managing neonatal sepsis in Nicaragua.实践中的质量：预防和管理尼加拉瓜新生儿败血症。
Int J Qual Health Care. 2013 Oct;25(5):599-605. doi: 10.1093/intqhc/mzt060. Epub 2013 Aug 20.
6
Management of neonates with suspected or proven early-onset bacterial sepsis.新生儿疑似或确诊早发性细菌败血症的处理。
Pediatrics. 2012 May;129(5):1006-15. doi: 10.1542/peds.2012-0541. Epub 2012 Apr 30.
7
[Neonatal sepsis].[新生儿败血症]
Duodecim. 2014;130(7):675-82.
8
Etiology and risk factors for early onset neonatal sepsis.早发型新生儿败血症的病因及危险因素
Indian J Med Microbiol. 2009 Jul-Sep;27(3):279. doi: 10.4103/0255-0857.53221.
9
Challenges in the diagnosis and management of neonatal sepsis.新生儿败血症诊断与管理中的挑战
J Trop Pediatr. 2015 Feb;61(1):1-13. doi: 10.1093/tropej/fmu079. Epub 2015 Jan 20.
10
Neonatal sepsis: progress towards improved outcomes.新生儿败血症：改善预后的进展。
J Infect. 2014 Jan;68 Suppl 1:S24-32. doi: 10.1016/j.jinf.2013.09.011. Epub 2013 Oct 18.

引用本文的文献

1
Early-onset neonatal sepsis in a Chinese maternal and child healthcare centre, 2017-2023.2017 - 2023年中国一家妇幼保健中心的早发型新生儿败血症
Front Pediatr. 2025 Apr 15;13:1521908. doi: 10.3389/fped.2025.1521908. eCollection 2025.
2
Microbial Infections and Antimicrobial Use in Neonates and Infants.新生儿和婴儿的微生物感染与抗菌药物使用
Trop Med Infect Dis. 2025 Mar 18;10(3):80. doi: 10.3390/tropicalmed10030080.
3
16S rDNA Sequencing for Bacterial Identification in Preterm Infants with Suspected Early-Onset Neonatal Sepsis.
16S核糖体DNA测序用于疑似早发型新生儿败血症早产儿的细菌鉴定
Trop Med Infect Dis. 2024 Jul 6;9(7):152. doi: 10.3390/tropicalmed9070152.
4
Early-Onset Sepsis as an Early Predictor for Retinopathy of Prematurity: A Meta-analysis.早发型败血症作为早产儿视网膜病变的早期预测指标：一项荟萃分析。
Am J Perinatol. 2025 Feb;42(3):387-394. doi: 10.1055/a-2369-6690. Epub 2024 Jul 19.
5
Hemoglobin, Ferritin, and Lactate Dehydrogenase as Predictive Markers for Neonatal Sepsis.血红蛋白、铁蛋白和乳酸脱氢酶作为新生儿败血症的预测标志物
J Pers Med. 2024 Apr 29;14(5):476. doi: 10.3390/jpm14050476.
6
Risk factors and etiology of early-onset neonatal sepsis in Northeastern part of India: Case-control study.印度东北部早发型新生儿败血症的危险因素及病因：病例对照研究
J Family Med Prim Care. 2024 Jan;13(1):54-58. doi: 10.4103/jfmpc.jfmpc_807_23. Epub 2024 Feb 8.
7
Association Between Hypoglycemia and the Occurrence of Early Onset Sepsis in Premature Infants.低血糖与早产儿早发性败血症发生的关系。
J Pediatric Infect Dis Soc. 2023 Dec 26;12(Supplement_2):S28-S36. doi: 10.1093/jpids/piad067.
8
Diagnostic Accuracy of Multiplex Polymerase Chain Reaction in Early Onset Neonatal Sepsis.多重聚合酶链反应在早发型新生儿败血症中的诊断准确性
Children (Basel). 2023 Nov 14;10(11):1809. doi: 10.3390/children10111809.
9
Bacterial Aetiology of Neonatal Sepsis and Antimicrobial Resistance Pattern at the Regional Referral Hospital, Dar es Salam, Tanzania; A Call to Strengthening Antibiotic Stewardship Program.坦桑尼亚达累斯萨拉姆地区转诊医院新生儿败血症的细菌病因及抗菌药物耐药模式；加强抗生素管理计划的呼吁
Antibiotics (Basel). 2023 Apr 16;12(4):767. doi: 10.3390/antibiotics12040767.
10
Patterns of Infections among Extremely Preterm Infants.极早早产儿的感染模式
J Clin Med. 2023 Apr 4;12(7):2703. doi: 10.3390/jcm12072703.