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健康与慢性牙周炎状态下颈部牙骨质三层结构的纳米结构评估：一项体外研究

Evaluation of the nanostructure of cervical third cementum in health and chronic periodontitis: An in vitro study.

作者信息

Sundaram Subramoniam, Ramaseshan Rajagopalan, Dash Sitaram, Rao Suresh Ranga

机构信息

Department of Periodontics, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.

Surface and Nanoscience Division, Thin Films and Coatings Section, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu, India.

出版信息

J Indian Soc Periodontol. 2014 Sep;18(5):560-6. doi: 10.4103/0972-124X.142440.

DOI:10.4103/0972-124X.142440
PMID:25425815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4239743/
Abstract

BACKGROUND

During the progression of periodontal disease, the cementum undergoes alterations in its structure and composition. Understanding the nanostructure of cementum, in terms of its mechanical properties, will provide an insight into the milieu that periodontal ligament cells encounter in health and chronic periodontitis. This study aims to analyze the nanomechanical properties of the cervical third of the cementum (transverse section) in health and chronic periodontitis.

MATERIALS AND METHODS

Twenty teeth (10 healthy and 10 periodontally diseased) were collected and the nanomechanical properties of the transverse section of the cervical third cementum were evaluated with depth-sensing nanoindentation technique under dry conditions. A total of 100 nanoindentations were performed to analyze the modulus of elasticity and hardness of cervical third of the cementum.

RESULTS

The nanomechanical properties of the healthy cervical third cementum sections were significantly higher (P < 0.05) (hardness: 0.720 ± 0.305 GPa; modulus: 15.420 ± 3.902 GPa) than the diseased cementum section (hardness: 0.422 ± 0.157 GPa; modulus: 11.056 ± 3.434 GPa).

CONCLUSION

The results of our study indicate that the hardness and modulus of elasticity of the cervical third cementum decreases significantly in chronic periodontitis.

摘要

背景

在牙周疾病进展过程中，牙骨质的结构和成分会发生改变。从机械性能方面了解牙骨质的纳米结构，将有助于深入了解牙周膜细胞在健康状态和慢性牙周炎中所面临的环境。本研究旨在分析健康和慢性牙周炎状态下牙骨质颈部三分之一（横切面）的纳米力学性能。

材料与方法

收集20颗牙齿（10颗健康牙齿和10颗牙周病牙齿），在干燥条件下采用深度传感纳米压痕技术评估牙骨质颈部三分之一横切面的纳米力学性能。共进行100次纳米压痕试验，以分析牙骨质颈部三分之一的弹性模量和硬度。

结果

健康牙骨质颈部三分之一切片的纳米力学性能（硬度：0.720±0.305吉帕；模量：15.420±3.902吉帕）显著高于患病牙骨质切片（硬度：0.422±0.157吉帕；模量：11.056±3.434吉帕）（P<0.05）。

结论

我们的研究结果表明，慢性牙周炎时牙骨质颈部三分之一的硬度和弹性模量显著降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/9548f04df564/JISP-18-560-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/a72bd1016049/JISP-18-560-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/5f3652694a33/JISP-18-560-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/6d660e72f890/JISP-18-560-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/d2dd3a63d99e/JISP-18-560-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/894a0f12879d/JISP-18-560-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/96b23aa7ba36/JISP-18-560-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/62fba2e376f0/JISP-18-560-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/9548f04df564/JISP-18-560-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/a72bd1016049/JISP-18-560-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/5f3652694a33/JISP-18-560-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/6d660e72f890/JISP-18-560-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/d2dd3a63d99e/JISP-18-560-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/894a0f12879d/JISP-18-560-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/96b23aa7ba36/JISP-18-560-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/62fba2e376f0/JISP-18-560-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca20/4239743/9548f04df564/JISP-18-560-g015.jpg

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