Guarascio Anthony J, Faust Andrew C, Sheperd Lyndsay, O'Donnell Lauren A
Mylan School of Pharmacy at Duquesne University, Pittsburgh, PA, USA
Texas Health Presbyterian Hospital, Dallas, TX, USA.
Ann Pharmacother. 2015 Feb;49(2):247-9. doi: 10.1177/1060028014561782. Epub 2014 Nov 26.
Ebola virus disease (EVD) poses significant clinical care implications for pharmacists. Emergency preparedness efforts should be undertaken to ensure vital response to EVD. Pharmacists should consider factors such as enhanced use of resources for front-line EVD patient care along with procurement of investigational medications. Appropriate and timely preparation, distribution, and administration of treatment for patients with EVD in the setting of substantial critical illness as well as infection control measures are essential. Aggressive supportive care and early, goal-directed therapy are cornerstones of therapy, whereas investigational treatments for EVD will likely play a larger, more well-defined role as future clinical trials are conducted.
埃博拉病毒病(EVD)对药剂师的临床护理工作具有重大影响。应开展应急准备工作,以确保对埃博拉病毒病做出至关重要的应对。药剂师应考虑一些因素,如增加用于一线埃博拉病毒病患者护理的资源,以及采购试验性药物。在患者病情严重以及采取感染控制措施的情况下,为埃博拉病毒病患者进行适当、及时的治疗准备、分发和给药至关重要。积极的支持性护理和早期目标导向治疗是治疗的基石,而随着未来开展临床试验,埃博拉病毒病的试验性治疗可能会发挥更大、更明确的作用。