Chin K Y, Panerai R B
Department of Medical Physics, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary , Leicester LE1 5WW , UK .
J Med Eng Technol. 2015 Jan;39(1):79-85. doi: 10.3109/03091902.2014.979953. Epub 2014 Nov 28.
Arterial volume clamping uses external compression of an artery to provide continuous non-invasive measurement of arterial blood pressure. It has been assumed that mean arterial pressure (MAP) corresponds to the point where unloading leads to the maximum oscillation of the arterial wall as reflected by photoplethysmogram (PPG), an assumption that has been challenged. Five subjects were recruited for the study (three males, mean age (SD) = 32 (15) years). The PPG waveform was analysed to identify the relationship between the external compressing pressure, PPG pulse amplitude and MAP. Two separate tests were carried out at compression step intervals of 10 mmHg and 2 mmHg, respectively. No significant differences were found between the two tests. The bias between the compressing pressure and the MAP was -4.7 ± 5.63 mmHg (p < 0.001) showing a normal distribution. Further research is needed to identify optimal algorithms for estimation of MAP using PPG associated with arterial compression.
动脉容积钳夹法通过对动脉进行外部压迫来实现对动脉血压的连续无创测量。一直以来，人们认为平均动脉压（MAP）对应于卸载导致动脉壁最大振荡的点，这一点可通过光电容积脉搏波描记图（PPG）反映出来，但这一假设受到了挑战。该研究招募了5名受试者（3名男性，平均年龄（标准差）= 32（15）岁）。分析PPG波形以确定外部压迫压力、PPG脉搏波幅度与MAP之间的关系。分别以10 mmHg和2 mmHg的压迫步长间隔进行了两项独立测试。两项测试之间未发现显著差异。压迫压力与MAP之间的偏差为 -4.7 ± 5.63 mmHg（p < 0.001），呈正态分布。需要进一步研究以确定使用与动脉压迫相关的PPG来估计MAP的最佳算法。
