一个作为研究防御素肽攻击工具的细菌突变体文库。
A bacterial mutant library as a tool to study the attack of a defensin peptide.
作者信息
Moser Simone, Chileveru Haritha R, Tomaras Jill, Nolan Elizabeth M
机构信息
Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA).
出版信息
Chembiochem. 2014 Dec 15;15(18):2684-8. doi: 10.1002/cbic.201402354. Epub 2014 Nov 27.
Abstract
Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.
摘要
防御素出击！在此我们报告了针对大肠杆菌基因敲除文库对人防御素5的筛选。该筛选结果进一步加深了我们对这种重要的宿主防御肽如何杀死细菌以及细菌如何保护自身免受人类宿主攻击的理解。
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