Yang Isaac, Ung Nolan, Chung Lawrance K, Nagasawa Daniel T, Thill Kimberly, Park Junmook, Tenn Stephen
Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Ste. 562, 5th Floor, Wasserman Bldg., Los Angeles, CA 90095-6901, USA.
Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Ste. 562, 5th Floor, Wasserman Bldg., Los Angeles, CA 90095-6901, USA; Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA.
Neurosurg Clin N Am. 2015 Jan;26(1):5-10. doi: 10.1016/j.nec.2014.09.011.
Central neurocytomas (CNs) are rare central nervous system tumors that occur in the lateral ventricles. They are prevalent in young adults and are typically benign with excellent prognosis following surgical resection. Because of the rarity of the disease and its similar features with more common tumors, misdiagnosis becomes an issue. Optimal treatment is achieved only when the correct tumor types are distinguished. Typical clinical manifestations include symptoms of increased intracranial pressure, although no clinical feature is pathognomonic to CN. Radiologic imaging, histology, magnetic resonance spectroscopy, and immunohistochemistry must be used to elucidate tumor characteristics and properly diagnose CN.
中枢神经细胞瘤(CNs)是发生于侧脑室的罕见中枢神经系统肿瘤。它们在年轻人中较为常见,通常为良性,手术切除后预后良好。由于该疾病罕见且与更常见肿瘤具有相似特征,误诊成为一个问题。只有区分出正确的肿瘤类型才能实现最佳治疗。典型临床表现包括颅内压升高症状,尽管没有临床特征对中枢神经细胞瘤具有确诊意义。必须使用放射影像学、组织学、磁共振波谱和免疫组织化学来阐明肿瘤特征并正确诊断中枢神经细胞瘤。