中枢神经细胞瘤的治疗：放射治疗

The management of central neurocytoma: radiotherapy.

作者信息

Barani Igor J, Raleigh David R, Larson David

机构信息

Department of Radiation Oncology, University of California, San Francisco, 505 Parnassus Avenue, Room L-08, San Francisco, CA 94143-0226, USA.

出版信息

Neurosurg Clin N Am. 2015 Jan;26(1):45-56. doi: 10.1016/j.nec.2014.09.014.

DOI:10.1016/j.nec.2014.09.014

PMID:25432183

Abstract

Intraventricular neurocytomas (IVNs) are rare tumors of neuronal differentiation, accounting for 0.1% to 0.5% of all primary brain tumors. Complete surgical resection is highly recommended, but at least one-third to one-half are subtotally resected. Stereotactic radiosurgery (SRS) and conventional radiotherapy have been used for management of residual and recurrent tumors, but the optimal treatment following subtotal surgical resection is less clear. Although there are trends toward higher local tumor control and survival rates with lower complications among IVNs treated with SRS, higher quality data are required to confirm these findings.

摘要

脑室内神经细胞瘤（IVNs）是一种罕见的具有神经元分化特征的肿瘤，占所有原发性脑肿瘤的0.1%至0.5%。强烈建议进行完整的手术切除，但至少三分之一至二分之一的病例只能进行次全切除。立体定向放射外科（SRS）和传统放疗已被用于治疗残留和复发性肿瘤，但次全手术切除后的最佳治疗方案尚不清楚。尽管接受SRS治疗的IVNs有局部肿瘤控制率更高、生存率更高且并发症更少的趋势，但仍需要更高质量的数据来证实这些发现。