Multidisciplinary approach in the management of gestational trophoblastic tumor (GTT).

In summary of our 15 years experiences it is obvious that at least about 15% of GTT patients still do not get complete remission in spite of development of multiagent chemotherapy. To obtain better therapeutical result in unceasing problems should be solved and the improvement in newer methods of management as listed below is mandatory: (1) Prediction on risk factors and early diagnosis of the persistent GTT before and after molar evacuation (2) "Clinico-biochemical classification" based on more collective tumor markers (3) New chemotherapeutic agents (4) Regimen for prevention and/or modulation of drug resistance (5) Multimodality treatment including initial and adjuvant surgery, irradiation and immune response modifiers. (6) Remission consolidation