[伴有广泛凝固性坏死及高血清CYFRA 21-1水平的胸腺瘤；一例报告]

[Thymoma with extensive coagulative necrosis and high serum level of CYFRA 21-1; report of a case].

作者信息

Himuro Naoya, Minakata Takao, Oshima Yutaka, Tomita Yuri, Kataoka Daisuke, Kadokura Mitsutaka

机构信息

Division of Chest Surgery, Showa University School of Medicine, Tokyo, Japan.

出版信息

Kyobu Geka. 2014 Dec;67(13):1205-7.

PMID:25434553

Abstract

A 73-year-old woman complained of right chest discomfort. Chest X-ray during the follow-up for rheumatoid arthritis showed a mediastinal tumor. Chest computed tomography (CT) and magnetic resonance imaging (MRI) showed a 65-mm tumor in the right anterior mediastinum. A blood test showed high serum levels of CYFRA 21-1(29.8 ng/ml), white blood cells( WBC 10,800/µl), and C-reactive protein(CRP 16.1 mg/dl). Subsequently, inflammatory reactions improved, and the thymic tumor was resected. Histopathologically, the tumor was a type B2 thymoma with extensive coagulative necrosis. After resection, the serum CYFRA 21-1 level returned to the normal range.

摘要

一名73岁女性主诉右胸不适。类风湿关节炎随访期间的胸部X线检查显示纵隔肿瘤。胸部计算机断层扫描（CT）和磁共振成像（MRI）显示右前纵隔有一个65毫米的肿瘤。血液检查显示血清CYFRA 21-1水平升高（29.8纳克/毫升）、白细胞（WBC 10,800/微升）和C反应蛋白（CRP 16.1毫克/分升）。随后，炎症反应改善，胸腺肿瘤被切除。组织病理学检查显示，该肿瘤为B2型胸腺瘤，伴有广泛的凝固性坏死。切除后，血清CYFRA 21-1水平恢复到正常范围。