胆管癌的诊断和预后血清标志物（综述）
Diagnostic and prognostic serum marker of cholangiocarcinoma (Review).
作者信息
Zeng Xiaojun, Tao Hualin
机构信息
Department of Laboratory Medicine, Luzhou Medical College, Luzhou, Sichuan 646000, P.R. China.
Department of Laboratory Medicine, Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan 646000, P.R. China.
出版信息
Oncol Lett. 2015 Jan;9(1):3-8. doi: 10.3892/ol.2014.2696. Epub 2014 Nov 10.
Cholangiocarcinoma (CCA) is a fatal disease that is typically diagnosed late and treated ineffectively. As the morbidity and mortality rates for CCA rise markedly, patietns with CCA currently have a poor prognosis. However, if it were possible to diagnose CCA early while effective treat methods are available, CCA patients would achieve a better quality of life. Therefore, preventing the process of CCA in the early stages is an urgent problem to solve. An accurate, quick and safe method to diagnose early-stage CCA is required. The present review discusses the risk factors, status of research and certain serum markers of CCA. The sensitivity and specificity of these markers differ from each other. To explore the more accurate serum markers may be a novel direction and method for the diagnosis of CCA in laboratory medicine in the future.
胆管癌（CCA）是一种致命疾病，通常诊断较晚且治疗效果不佳。随着CCA发病率和死亡率显著上升，目前CCA患者的预后较差。然而，如果能够在有有效治疗方法时早期诊断CCA，CCA患者将获得更好的生活质量。因此，在早期阶段预防CCA的进程是一个亟待解决的问题。需要一种准确、快速且安全的方法来诊断早期CCA。本综述讨论了CCA的危险因素、研究现状及某些血清标志物。这些标志物的敏感性和特异性各不相同。探索更准确的血清标志物可能是未来检验医学中诊断CCA的一个新方向和方法。
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