Department of Otorhinolaryngology, University of Rome Tor Vergata, Rome, Itlay.
Department of Hematology, University of Rome Tor Vergata, Rome, Itlay.
Clin Exp Otorhinolaryngol. 2014 Dec;7(4):302-6. doi: 10.3342/ceo.2014.7.4.302. Epub 2014 Nov 14.
In onco-hematological diseases, the incidence of paranasal sinuses infection dramatically increase and requires a combination of medical and surgical therapy. Balloon dilatation surgery (DS) is a minimally invasive, tissue preserving procedure. The study evaluates the results of DS for rhinosinusitis in immunocompromised patients.
A retrospective chart review was conducted in 110 hematologic patients with rhinosinusitis. Twenty-five patients were treated with DS technique and 85 patients with endoscopic sinus surgery (ESS). We considered the type of anesthesia and the extent of intra- and postoperative bleeding. Patients underwent Sino-Nasal Outcome Test (SNOT-20) to evaluate changes in subjective symptoms and global patient assessment (GPA) questionnaire to value patient satisfaction.
Local anesthesia was employed in 8 cases of DS and in 15 of ESS. In 50 ESS patients, an anterior nasal packing was placed and in 12 cases a repacking was necessary. In the DS group, nasal packing was required in 8 cases and in 2 cases a repacking was placed (P=0.019 and P=0.422, respectively). The SNOT-20 change score showed significant improvement of health status in both groups. However the DS group showed a major improvement in 3 voices: need to blow nose, runny nose, and facial pain/pressure. The 3-month follow-up GPA questionnaire showed an higher satisfaction of DS group.
Balloon DS represents a potentially low aggressive treatment and appears to be relatively safe and effective in onco-hematologic patients. All these remarks may lead the surgeon to consider a larger number of candidates for surgical procedure.
在肿瘤血液病中,鼻窦感染的发病率显著增加,需要结合内科和外科治疗。球囊扩张术(DS)是一种微创、保留组织的手术。本研究评估了 DS 治疗免疫功能低下患者鼻窦炎的效果。
对 110 例患有鼻窦炎的血液病患者进行回顾性图表分析。25 例患者采用 DS 技术治疗,85 例患者采用内镜鼻窦手术(ESS)治疗。我们考虑了麻醉类型和术中和术后出血的程度。患者接受 Sino-Nasal Outcome Test(SNOT-20)以评估主观症状的变化和全球患者评估(GPA)问卷以评估患者满意度。
DS 中有 8 例采用局部麻醉,ESS 中有 15 例采用局部麻醉。在 50 例 ESS 患者中,前鼻孔填塞 15 例,12 例需要重新填塞。在 DS 组中,8 例需要鼻腔填塞,2 例需要重新填塞(P=0.019 和 P=0.422)。SNOT-20 变化评分显示两组患者健康状况均有显著改善。然而,DS 组在 3 个方面有明显改善:需要擤鼻子、流鼻涕和面部疼痛/压力。3 个月的随访 GPA 问卷显示 DS 组的满意度更高。
球囊 DS 代表一种潜在的低侵袭性治疗方法,对于肿瘤血液病患者似乎是安全有效的。所有这些都可能导致外科医生考虑更多的手术候选人。