1 Radiation Oncology, 2 Pathology, Post Graduate Institute of Medical Sciences, Rohtak, India ; 3 Radiation Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India ; 4 Hospital Administration, All India Institute of Medical Sciences, New Delhi, India.
J Gastrointest Oncol. 2014 Dec;5(6):E125-7. doi: 10.3978/j.issn.2078-6891.2014.063.
Lymphoma of the mucosa-associated lymphoid tissue (MALT) has been used to describe a marginal zone B-cell lymphoma derived from gastrointestinal lymphoid tissue. mucosa-associated lymphoid tissue lymphoma (MALToma) of the ileum are extremely rare and only few reports with endoscopic features have been reported.
We present a 55-year-old male patient with history of abdominal pain and loss of appetite since 2½ years. Abdomino-pelvic ultrasonography was normal, but computed tomography (CT) scan of the abdomen showed, dilated segment of ileum containing both contrast and debris. He underwent segmental resection of ileum associated with stricture site, histopathology of which revealed MALToma of ileum. Patient was subsequently treated with low dose chemotherapy and strictly followed up.
Primary treatment possibility should be considered as the treatment of H. pylori infection while surgical resection for superficial lesions followed by low dose chemotherapy is recommended. The present case report explore MALToma of the GI tract, its diagnostic criterions, role of radiological and pathological tools, various investigative techniques and role of surgery and chemotherapy in such cases.
黏膜相关淋巴组织(MALT)淋巴瘤曾被用来描述一种来源于胃肠道淋巴组织的边缘区 B 细胞淋巴瘤。回肠黏膜相关淋巴组织淋巴瘤(MALToma)极为罕见,仅有少数报道涉及内镜特征。
我们报告了一名 55 岁男性患者,他有 2 年半的腹痛和食欲不振病史。腹部超声检查正常,但腹部 CT 扫描显示回肠扩张段含有对比剂和碎片。他接受了回肠节段切除术和狭窄部位切除术,组织病理学显示为回肠 MALToma。随后,患者接受了低剂量化疗,并进行了严格的随访。
应考虑作为幽门螺杆菌感染的主要治疗可能性,而对于浅表病变,建议行手术切除,然后进行低剂量化疗。本病例报告探讨了胃肠道 MALToma,其诊断标准,影像学和病理学工具的作用,各种检查技术以及手术和化疗在这些病例中的作用。