智利某三级医疗中心葡萄膜炎的病因：一项横断面回顾性研究。
Causes of Uveitis in a Tertiary Center in Chile: A Cross-sectional Retrospective Review.
作者信息
Liberman Paulina, Gauro Fuad, Berger Osvaldo, Urzua Cristhian A
机构信息
a Faculty of Medicine , Universidad de Chile , Santiago , Chile.
b Ophthalmology Department, Faculty of Medicine , Pontificia Universidad Católica de Chile , Santiago , Chile , and.
出版信息
Ocul Immunol Inflamm. 2015 Aug;23(4):339-345. doi: 10.3109/09273948.2014.981548. Epub 2014 Dec 1.
PURPOSE
To describe the pattern of uveitis in a tertiary center in Santiago, Chile.
METHODS
We reviewed all of the case records with a presumptive diagnosis of uveitis from patients referred to the Uveitis Department of Hospital del Salvador between 2002 and 2012. Initial assessment was standardized. We tested for association among causes, gender, and age groups.
RESULTS
Anterior uveitis was the leading anatomical location of the inflammation (40.4%). A specific etiology was demonstrated in 59% of cases (28.7% infectious). Vogt-Koyanagi-Harada syndrome (VKH) was the most frequent cause of uveitis (17.2%). We found association between idiopathic intermediate uveitis, toxocariasis, juvenile idiopathic arthritis, VKH, toxoplasmosis, diabetes mellitus (DM)-associated uveitis, tuberculosis, and idiopathic anterior uveitis and age groups. VKH, DM-associated uveitis, and syphilis-associated uveitis were associated with gender.
CONCLUSIONS
Our sample shows a distribution of causes of uveitis similar to those in developed countries. The prevalence of VKH is higher than expected.
目的
描述智利圣地亚哥一家三级医疗中心葡萄膜炎的发病模式。
方法
我们回顾了2002年至2012年间转诊至萨尔瓦多医院葡萄膜炎科的所有疑似葡萄膜炎患者的病例记录。初始评估采用标准化方法。我们检测了病因、性别和年龄组之间的关联性。
结果
前葡萄膜炎是炎症的主要解剖部位（40.4%）。59%的病例显示有特定病因（28.7%为感染性病因）。伏格特-小柳-原田综合征（VKH）是葡萄膜炎最常见的病因（17.2%）。我们发现特发性中间葡萄膜炎、弓蛔虫病、幼年特发性关节炎、VKH、弓形虫病、糖尿病（DM）相关性葡萄膜炎、结核病和特发性前葡萄膜炎与年龄组之间存在关联。VKH、DM相关性葡萄膜炎和梅毒相关性葡萄膜炎与性别有关。
结论
我们的样本显示葡萄膜炎病因分布与发达国家相似。VKH的患病率高于预期。
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