Siddiqui M Shadab, Stravitz R Todd
Section of Hepatology, Hume-Lee Transplant Center, Virginia Commonwealth University, 1200 East Broad Street, Richmond, VA 23222, USA.
Section of Hepatology, Hume-Lee Transplant Center, Virginia Commonwealth University, 1200 East Broad Street, Richmond, VA 23222, USA.
Clin Liver Dis. 2014 Nov;18(4):957-78. doi: 10.1016/j.cld.2014.07.012. Epub 2014 Sep 6.
Acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) usually mandate management within an intensive care unit (ICU). Even though the conditions bear some similarities, precipitating causes, and systemic complications management practices differ. Although early identification of ALF and ACLF, improvements in ICU management, and the widespread availability of liver transplantation have improved mortality, optimal management practices have not been defined. This article summarizes current ICU management practices and identifies areas of management that require further study.
急性肝衰竭(ALF)和慢加急性肝衰竭(ACLF)通常需要在重症监护病房(ICU)进行治疗。尽管这两种病症有一些相似之处,但引发原因和全身并发症的管理方法有所不同。虽然对ALF和ACLF的早期识别、ICU管理的改善以及肝移植的广泛应用已降低了死亡率,但尚未确定最佳的管理方法。本文总结了当前ICU的管理方法,并确定了需要进一步研究的管理领域。