肠道黏膜个体发育及肿瘤转化过程中膜受体和（原）癌基因的表达。
Expression of membrane receptors and (proto)oncogenes during the ontogenic development and neoplastic transformation of the intestinal mucosa.
作者信息
Chastre E, Emami S, Gespach C
机构信息
INSERM U.55, Unité de Recherches sur les Peptides Neurodigestifs et le Diabète, Hôpital Saint-Antoine, Paris, France.
出版信息
Life Sci. 1989;44(23):1721-42. doi: 10.1016/0024-3205(89)90560-2.
PMID:2543878
Abstract
The functional relationship between membrane receptors involved in signal transduction and (proto) oncogene expression has been explored during the ontogenic development and differentiation of the intestinal mucosa in man and rat. The present review develops detailed picture of the current understanding of some mechanisms underlying growth and function of normal, immortalized and cancerous intestinal epithelial cells.
摘要
在人类和大鼠肠道黏膜的个体发育及分化过程中，已对参与信号转导的膜受体与（原）癌基因表达之间的功能关系进行了探索。本综述详细阐述了目前对正常、永生化及癌性肠上皮细胞生长和功能的某些潜在机制的理解。
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