Synthesis of novel binary and ternary complexes derived from 1-(2-hydroxy benzoyl)-4-phenylthiosemicarbazide (L(1)) and 2,2'-dipyridyl (L(2)) with Co(II), Cu(II) and Zn(II) salts.

The complexes derived the reactions of 1-(2-hydroxybenzoyl)-4-phenylthiosemicarbazide (L(1)) with MX2 (M = Co(II), Cu(II) and Zn(II) ions; X = Cl(-) in case of Co(II) and Cu(II) ions, Cl(-) and Ac(-) in case of Zn(II)) in EtOH, were synthesized and characterized. The results suggested that the complexes have the general formulae, [Cu(L(1)-2H)(EtOH)(H2O)2]⋅H2O, [Co(L(1)-2H)(EtOH)(H2O)]⋅2H2O and [Zn(L(1)-2H)(EtOH)]. Also, the ternary complexes, derived from the reactions 2,2'-dipyridyl (L(2)) with the metals salts followed by adding a solution of the L(1) were synthesized and having the general formulae, [Cu2(L(2))(L(1)-2H)(H2O)(OH)2]⋅1/2H2O, [Co(L(2))(L(1)-2H)]⋅1.5EtOH⋅3H2O and [Zn(L(2))(L(1)-2H)]⋅EtOH. The binary and ternary complexes were characterized by elemental analyses, molar conductivities, spectral (IR, UV-Vis, (1)H-NMR and mass), thermal and magnetic measurements. The existence of OH group in the ternary complexes was confirmed by IR spectra. The amounts of solvent were determined from the results of TGA. The biological activity for the ligand and two complexes were tested against DNA.