Schwarz T F, Roggendorf M
Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie der L.-M.-Universität München.
Z Hautkr. 1989 Apr 15;64(4):272-3.
Human parvovirus B19 is the causative agent of erythema infectiosum and other atypical (rubelliform) exanthemas. On account of the relatively high prevalence of B19, these infections are rather frequent. They usually occur during childhood, but also up to the age of 30, and there are various clinical manifestations. During pregnancy, B19 infection may cause hydrops of the fetus with ensuing fetal death. Anti-B19 IgM and IgG can be detected by means of ELISA or RIA; B19-DNA is identified by hybridization of nucleic acid.
人细小病毒B19是传染性红斑及其他非典型（风疹样）皮疹的病原体。由于B19的感染率相对较高，这些感染相当常见。它们通常发生在儿童期，但也可发生在30岁之前，并且有多种临床表现。在孕期，B19感染可能导致胎儿水肿并继而造成胎儿死亡。抗B19 IgM和IgG可通过ELISA或RIA检测；B19-DNA通过核酸杂交来鉴定。
