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[人类生物学衰老的客观评估:结果]

[Objective assessment of biological aging in the human: results].

作者信息

Ruiz-Torres A, Agudo A, Holzenberger M, Beier W

机构信息

Instituto Universitario de Investigación Gerontológica y Metabólica de la Universidad Autónoma de Madrid, Spain.

出版信息

Z Gerontol. 1989 Mar-Apr;22(2):85-9.

PMID:2544063
Abstract

From a population sample of 139 healthy persons, six specially selected aging parameters were tested for their significance to vitality, by means of four mathematical models referring to the concept of vitality. As reference values, tm, is the age expressed in years when maximal vitality occurs, and the aging constant is beta, also known as an aging factor. Our results for tm extended from 16.6 to 39.6 years, depending on the respective mathematical model applied. We find a similar characteristic for the beta-values. A comparison with results in other publications on the subject, obtained by processing a considerably larger number of variables than we did, underlined the utility of our parameters. This is also shown by the quality of results we obtained by regression analysis, by the adjustment to the functions of the vitality concept and by the simplicity of the required laboratory methods of analysis.

摘要

从139名健康人的总体样本中,通过四个与活力概念相关的数学模型,对六个特别选定的衰老参数进行了活力显著性测试。作为参考值,tm是出现最大活力时以年为单位表示的年龄,衰老常数为β,也称为衰老因子。根据所应用的各自数学模型,我们得出的tm结果在16.6岁至39.6岁之间。我们发现β值也有类似特征。与该主题其他出版物的结果进行比较,那些研究处理的变量数量比我们多得多,这突出了我们参数的实用性。我们通过回归分析获得的结果质量、对活力概念函数的拟合以及所需实验室分析方法的简单性也证明了这一点。

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